Protein Alignment Ser7 and HP

DIOPT Version :9

• Sequence 1: NP_572582.1
• Gene: Ser7 / 31917
• FlyBaseID: FBgn0019929
• Length: 397
• Species: Drosophila melanogaster
• Sequence 2: NP_005134.1
• Gene: HP / 3240
• HGNCID: 5141
• Length: 406
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 88/306 - (28%)
• Similarity: 134/306 - (43%)
• Gaps: 65/306 - (21%)

  Fly   116 DQLPE-HPYCGSAFS-----FRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLT 174
            |:||| ...||...:     .|::|||......|||    :.:.|| ..:...||:.|.::||||
Human   140 DKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPW----QAKMVS-HHNLTTGATLINEQWLLT 199

  Fly   175 AAHCIHTMGRNLTAAILGEWNRDTDPDCENDLN---GVRECAPPHIRVTIDRILPHAQYSELNYR 236
            .|       :||   .|......|..|....|.   |.::.      |.|::::.|..||::
Human   200 TA-------KNL---FLNHSENATAKDIAPTLTLYVGKKQL------VEIEKVVLHPNYSQV--- 245

  Fly   237 NDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHI 301
             ||.|::|.:.|:  ..:.:.|:|||.:  .||.  .|....|||||:..:...:...:..||.:
Human   246 -DIGLIKLKQKVS--VNERVMPICLPSK--DYAE--VGRVGYVSGWGRNANFKFTDHLKYVMLPV 303

  Fly   302 QPQDQCQEAFYKDT---KIT----------LADSQMCAG-GEIGVDSCSGDSGGPLTV---EANT 349
            ..||||...:...|   |.|          |.:...||| .:...|:|.||:|....|   |.:|
Human   304 ADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDT 368

  Fly   350 ASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIRAN 395
                  .|..|::|.. |.|..|.: |:|.:|:|..||::.||..|
Human   369 ------WYATGILSFD-KSCAVAEY-GVYVKVTSIQDWVQKTIAEN 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/276 (28%)
		Tryp_SPc	133..391	CDD:238113	78/277 (28%)
HP	NP_005134.1	CCP	33..87	CDD:153056
		CCP	92..146	CDD:153056	4/5 (80%)
		Tryp_SPc	161..399	CDD:214473	78/276 (28%)
		Tryp_SPc	162..402	CDD:238113	78/278 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910