DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Klk15

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_777354.1	Gene:	Klk15 / 317652	MGIID:	2447533	Length:	254	Species:	Mus musculus

Alignment Length:	264	Identity:	90/264 - (34%)
Similarity:	118/264 - (44%)	Gaps:	57/264 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 PWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWN-RDTDPDCENDLN 207
            ||...| :|.   |: :.|||..|:.||:||||||.....|    ..|||.| |..|
Mouse    32 PWQVAL-FER---GR-FNCGAFLISPRWVLTAAHCQTRFMR----VRLGEHNLRKFD-------- 79

  Fly   208 GVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQL 272
                 .|..:| ::.||:||..|....:|:||.||||.:|......  :.||.||.:     ..|
Mouse    80 -----GPEQLR-SVSRIIPHPGYEARTHRHDIMLLRLFKPARLTAY--VRPVALPRR-----CPL 131

  Fly   273 AGSAADVSGWG-----KTESSGSSK--IKQKAMLH-----IQPQDQCQEAFYKDTKITLADSQMC 325
            .|....|||||     ...::||.|  ::....||     |..:..|.    ||....:..:.:|
Mouse   132 IGEDCVVSGWGLLSDNNPGATGSQKSHVRLPDTLHCANISIISEASCN----KDYPGRVLPTMVC 192

  Fly   326 AGGE-IGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIE 389
            ||.| .|.|||.|||||||....         .|.|:||.|...|.|....|:||:|.||::||.
Mouse   193 AGVEGGGTDSCEGDSGGPLVCGG---------ALQGIVSWGDVPCDTTTKPGVYTKVCSYLEWIW 248

  Fly   390 STIR 393
            ..:|
Mouse   249 ENVR 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	87/257 (34%)
		Tryp_SPc	133..391	CDD:238113	89/260 (34%)
Klk15	NP_777354.1	Tryp_SPc	23..247	CDD:238113	87/257 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910