DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	83/279 - (29%)
Similarity:	137/279 - (49%)	Gaps:	47/279 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CG--SAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTM--GR 184
            ||  :.:|.|:|||:.:.|.::||...|:::..     :.||.|.|...|::|||||::.:  .:
  Rat   207 CGMRTGYSPRIVGGNVSSLTQWPWQVSLQFQGY-----HLCGGSVITPLWIVTAAHCVYDLYHPK 266

  Fly   185 NLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVN 249
            :.|..: |..:....|            .|.|:   :::|:.|::|......|||||::||.|:.
  Rat   267 SWTVQV-GLVSLMDSP------------VPSHL---VEKIIYHSKYKPKRLGNDIALMKLSEPLT 315

  Fly   250 WLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTE--SSGSSKIKQKAMLHIQPQDQCQEAFY 312
            :  .:.::|:|||.....:.:   |.....||||.||  :..:|.:...|.:.:.....|.   :
  Rat   316 F--DETIQPICLPNSEENFPD---GKLCWTSGWGATEDGAGDASPVLNHAAVPLISNKICN---H 372

  Fly   313 KDT-KITLADSQMCAG---GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTAL 373
            :|. ...::.|.:|||   |  |||||.|||||||..:.     .|...|.|..|.| ..|....
  Rat   373 RDVYGGIISPSMLCAGYLKG--GVDSCQGDSGGPLVCQE-----RRLWKLVGATSFG-IGCAEVN 429

  Fly   374 FSGIYTRVSSYMDWIESTI 392
            ..|:|||::|::|||...:
  Rat   430 KPGVYTRITSFLDWIHEQL 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/264 (30%)
		Tryp_SPc	133..391	CDD:238113	79/265 (30%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	2/3 (67%)
		Tryp_SPc	216..444	CDD:214473	78/264 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910