DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss30

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_011244785.1	Gene:	Prss30 / 30943	MGIID:	1353645	Length:	347	Species:	Mus musculus

Alignment Length:	301	Identity:	87/301 - (28%)
Similarity:	130/301 - (43%)	Gaps:	64/301 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 DQLPEHPYCG-SAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCI 179
            |.||.  .|| |..:.::|||.:....::||...| :.|..|   :.||.|.|.:.|:||||||.
Mouse    59 DILPS--VCGHSRDAGKIVGGQDALEGQWPWQVSL-WITEDG---HICGGSLIHEVWVLTAAHCF 117

  Fly   180 ---------HTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPH-IRVTIDRILPHAQYSELN 234
                     |.....||.::|                      .|| ..|.:..|..|..|...:
Mouse   118 RRSLNPSFYHVKVGGLTLSLL----------------------EPHSTLVAVRNIFVHPTYLWAD 160

  Fly   235 YRN-DIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAM 298
            ..: ||||::|..|   |:.....|||||..:   .....|:...|:|||.|:....:.:.|:..
Mouse   161 ASSGDIALVQLDTP---LRPSQFTPVCLPAAQ---TPLTPGTVCWVTGWGATQERDMASVLQELA 219

  Fly   299 LHIQPQDQCQEAFY------KDTKITLADSQMCAGGEIG-VDSCSGDSGGPLTVEANTASGNRYV 356
            :.:...:.|::.::      ...:|..:| .:|||...| .|||.|||||||....|::...
Mouse   220 VPLLDSEDCEKMYHTQGSSLSGERIIQSD-MLCAGYVEGQKDSCQGDSGGPLVCSINSSWTQ--- 280

  Fly   357 YLAGVVS--IGRKHCGTALFSGIYTRVSSYMDWIESTIRAN 395
              .|:.|  ||   |......|:||||.:|:|||:..:..|
Mouse   281 --VGITSWGIG---CARPYRPGVYTRVPTYVDWIQRILAEN 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/276 (28%)
		Tryp_SPc	133..391	CDD:238113	80/277 (29%)
Prss30	XP_011244785.1	Tryp_SPc	74..312	CDD:238113	80/278 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910