DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and Ovch2

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_003749007.2	Gene:	Ovch2 / 308919	RGDID:	1564636	Length:	579	Species:	Rattus norvegicus

Alignment Length:	306	Identity:	86/306 - (28%)
Similarity:	133/306 - (43%)	Gaps:	71/306 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 PYCG------------SAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLT 174
            |.||            |.|| |:|||.......:||...|:.:     :.:.||.:.|:.:|::|
  Rat    31 PDCGKSLVKPWPQNYFSLFS-RIVGGSQVEKGSYPWQVSLKQK-----QKHICGGTIISSQWVIT 89

  Fly   175 AAHCIH----TMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYS---E 232
            ||||:.    .:..|:||.             |:||:   :..|....:.|:.|:.|.|:|   .
  Rat    90 AAHCMANRNIALTLNVTAG-------------EHDLS---QAEPGEQTLAIETIIIHPQFSTKKP 138

  Fly   233 LNYRNDIALLRLSRPVNWLQM-QNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGS-SKIKQ 295
            :||  |||||::   |...|. |.:.|||| |:.|...|  ||.....:|||:....|| .::.|
  Rat   139 MNY--DIALLKM---VGTFQFGQFVRPVCL-PEPGEQFN--AGYICTTAGWGRLSEGGSLPQVLQ 195

  Fly   296 KAMLHIQPQDQCQEAFYKDTKITLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLA 359
            :..|.|...::|:.............:.:|.|. :.|.|:|.|||||.|..:....:..    ||
  Rat   196 QVNLPILTHEECEAVMLTLRNPITGKTFLCTGSPDGGRDACQGDSGGSLMCQNRKGAWT----LA 256

  Fly   360 GVVSIG------------RKHCGTALFSGIYTRVSSYMDWIESTIR 393
            ||.|.|            :|..|:   .||:|.:...:.||...::
  Rat   257 GVTSWGLGCGRSWRNNARKKEQGS---PGIFTDLRRVLPWIHEHVQ 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/278 (28%)
		Tryp_SPc	133..391	CDD:238113	79/279 (28%)
Ovch2	XP_003749007.2	Tryp_SPc	52..297	CDD:238113	79/280 (28%)
		CUB	317..420	CDD:238001
		CUB	431..541	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910