DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Klk14

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_038956840.1	Gene:	Klk14 / 308562	RGDID:	1308606	Length:	310	Species:	Rattus norvegicus

Alignment Length:	320	Identity:	90/320 - (28%)
Similarity:	130/320 - (40%)	Gaps:	78/320 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 PRPPSGIDQLPEHP------YCGSAFSF-------------------RLVGGHNTGLFEFPWTTL 148
            |:|.||:....||.      ..||....                   :::||:.......||...
  Rat    36 PKPSSGLCGEQEHMGFLQTWTSGSRMLLLLTILQALAVAIVQSQGDDKILGGYTCVQNSQPWQVA 100

  Fly   149 LEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVR--E 211
            |:   ...|:.:.||...::.:|::|||||    .|.|....||:.|             :|  |
  Rat   101 LQ---AGPGRRFLCGGVLLSDQWVITAAHC----ARPLLHVALGKHN-------------LRRWE 145

  Fly   212 CAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPV---CLPPQRGRYANQLA 273
            .....:||.  |.:||.||....:.||:.||:|.|.|...:.....||   |..|
  Rat   146 ATQQVLRVV--RQVPHPQYRPQAHDNDLMLLKLQRKVRLGRAVRTIPVARSCASP---------- 198

  Fly   274 GSAADVSGWGKTESS--GSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAG-GEIGVDSC 335
            |:...|||||.|.|.  ......|...::|.|:..|..|:    ..|:....:||| .|.|.|||
  Rat   199 GTPCRVSGWGTTASPIVRYPTALQCVNVNIMPEQVCHRAY----PGTITSGMVCAGVPEGGKDSC 259

  Fly   336 SGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIRAN 395
            .|||||||..:..         |.|:||.|.:.|....:.|:||.:.:|..||:.|:::|
  Rat   260 QGDSGGPLVCQGQ---------LQGLVSWGMERCAMPGYPGVYTNLCNYHSWIQRTMQSN 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/264 (30%)
		Tryp_SPc	133..391	CDD:238113	80/265 (30%)
Klk14	XP_038956840.1	Tryp_SPc	84..306	CDD:238113	80/266 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910