DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Tmprss11e

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_038948843.1	Gene:	Tmprss11e / 305265	RGDID:	1561698	Length:	444	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	86/267 - (32%)
Similarity:	124/267 - (46%)	Gaps:	41/267 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 SFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGE 193
            |.|:|||.:....|:||.:.|:::     ..:.|||:.|:..||::||||..|
  Rat   210 SVRIVGGTSAEEGEWPWQSSLQWD-----GSHRCGATLISNTWLVSAAHCFRT------------ 257

  Fly   194 WNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEP 258
               ..||.......|. ...||.:...|.||:.|.:|:..::..||||:.|||||.....  :..
  Rat   258 ---HKDPSRWTASFGA-TLQPPKLTTGIRRIIVHEKYNYPSHDYDIALVELSRPVPCTNA--VHK 316

  Fly   259 VCLPPQRGRYANQLAGSAADVSGWGKTESSGSSK--IKQKAMLHIQPQDQCQEAFYKDTKITLAD 321
            ||||.....:.   .|....|:|:|...:.|.::  ::|..:.:|..|...:...|..   .:..
  Rat   317 VCLPDANHEFQ---PGQRMFVTGFGALRNDGFAQNYLRQVQVDYIDTQTCNRPQSYNG---AITP 375

  Fly   322 SQMCAG---GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSS 383
            ..:|||   ||  .|:|.|||||||.    |.......|||||||.| ..||.....|:||||::
  Rat   376 RMLCAGFLKGE--KDACQGDSGGPLV----TPDVRDVWYLAGVVSWG-DECGQPNKPGVYTRVTA 433

  Fly   384 YMDWIES 390
            :.|||.|
  Rat   434 FRDWITS 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	82/261 (31%)
		Tryp_SPc	133..391	CDD:238113	84/263 (32%)
Tmprss11e	XP_038948843.1	SEA	71..176	CDD:396113
Tmprss11e	XP_038948843.1	Tryp_SPc	213..441	CDD:238113	84/264 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910