DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss22

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001100454.1	Gene:	Prss22 / 302971	RGDID:	1310880	Length:	307	Species:	Rattus norvegicus

Alignment Length:	332	Identity:	81/332 - (24%)
Similarity:	139/332 - (41%)	Gaps:	66/332 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 PPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFSF-RLVGGHNTGLFEFP 144
            ||||        .......||.||...|.........:...|.||..... |:|||.::...::|
  Rat     6 PPLA--------LGGDQFRTLILLVLLTSTATVSAANIRGSPDCGKPQQLNRVVGGEDSADAQWP 62

  Fly   145 WTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLT-----AAILGEWNRDTDPDCEN 204
            |...:    :..|..: |..|.:..||:::||||..:   |:.     :.:||.|.
  Rat    63 WIVSI----LKNGSHH-CAGSLLTNRWVVSAAHCFSS---NMDKPSPYSVLLGAWK--------- 110

  Fly   205 DLNGVRECAPPHIRVTIDRILPHAQYSELNYRN-DIALLRLSRPVNWLQMQNLEPVC-------L 261
                :....|...:|.|..:|||.:||.....: ||||:||.||:.:  .:.:.|:|       |
  Rat   111 ----LGNPGPRSQKVGIASVLPHPRYSRKEGTHADIALVRLERPIQF--SERILPICLPDSSVHL 169

  Fly   262 PPQRGRYANQLAGSAADVSGWGKTESS---GSSKIKQKAMLHIQPQDQCQEAFYKDT-KITLADS 322
            ||....:          ::|||..:..   ...:..||..:.|...:.|:..:::.. :..:.:.
  Rat   170 PPNTNCW----------IAGWGSIQDGVPLPRPQTLQKLKVPIIDPELCKSLYWRGAGQEAITED 224

  Fly   323 QMCAGGEIGV-DSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMD 386
            .:|||...|. |:|.|||||||..:.:.     :..|.|::|.| :.|......|:||.:.::..
  Rat   225 MLCAGYLEGKRDACLGDSGGPLMCQVDD-----HWLLTGIISWG-EGCAERNRPGVYTSLLAHRP 283

  Fly   387 WIESTIR 393
            |::..::
  Rat   284 WVQRIVQ 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	68/274 (25%)
		Tryp_SPc	133..391	CDD:238113	68/275 (25%)
Prss22	NP_001100454.1	Tryp_SPc	49..285	CDD:214473	68/274 (25%)
Prss22	NP_001100454.1	Tryp_SPc	50..288	CDD:238113	68/276 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910