DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss32

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001100453.1	Gene:	Prss32 / 302970	RGDID:	1311905	Length:	334	Species:	Rattus norvegicus

Alignment Length:	330	Identity:	93/330 - (28%)
Similarity:	149/330 - (45%)	Gaps:	57/330 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 IIPPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCG-SAFSFRLVGGHNTGLFE 142
            |:..|.|.:..|:...|:.:.:|.   ..|.|....:|.:     || ...|.|:|.|.|..|.:
  Rat     8 ILYTLLPGVLLGSEVLTTDSYSLS---TQTGRSSIDLDSV-----CGRPRASGRIVSGQNAQLGQ 64

  Fly   143 FPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCI----HTMGRNLTAAILGEWNRDTDPDCE 203
            :||...:..:.|     :.||.|.|::.|:||||||.    |.....:....:..:..|.:|
  Rat    65 WPWQVSVREDGV-----HVCGGSLISEDWVLTAAHCFNQDQHLSAYTVLLGTISSYPEDNEP--- 121

  Fly   204 NDLNGVRECAPPHIRVTIDRILPHAQYS-ELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGR 267
            .:|..|.:            .:.:..|| |.:...|||||:|:.|:::  ...:.|||||    :
  Rat   122 RELRAVAQ------------YIKYPSYSAEEHSSGDIALLQLASPISF--NDYMLPVCLP----K 168

  Fly   268 YANQL-AGSAADVSGWGKTESSGSSK---IKQKAMLHIQPQDQC----QEAFYKDTKITLADSQM 324
            ..:.| .|:...|:|||...::....   ..|:..:.:.....|    ||.....|:..:.:..:
  Rat   169 PGDPLDPGTMCWVTGWGNIATNQPLPPPFTLQELQVPLIDAKTCNTYYQENSVPSTEQVILEDML 233

  Fly   325 CAGGEIG-VDSCSGDSGGPLTVEANTASGNRYVYL-AGVVSIGRKHCGTALFSGIYTRVSSYMDW 387
            |||...| .|:|:|||||||..:.|.      |:: |||||.| ..|..:...|:||.||.|:.|
  Rat   234 CAGFVEGKKDACNGDSGGPLVCDVND------VWIQAGVVSWG-SDCALSNRPGVYTNVSVYISW 291

  Fly   388 IESTI 392
            |::|:
  Rat   292 IQNTM 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/271 (29%)
		Tryp_SPc	133..391	CDD:238113	79/272 (29%)
Prss32	NP_001100453.1	Tryp_SPc	53..292	CDD:214473	78/271 (29%)
Prss32	NP_001100453.1	Tryp_SPc	54..295	CDD:238113	79/273 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910