DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001121000.1	Gene:	Tmprss13 / 300682	RGDID:	1310872	Length:	539	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	88/279 - (31%)
Similarity:	135/279 - (48%)	Gaps:	39/279 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 YCG-SAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNL 186
            :|| .|.:.|:|||..|...::||...|.:     |..:.||.:.|..:|:||||||.......
  Rat   288 HCGLRAMTGRIVGGALTSESKWPWQVSLHF-----GTTHICGGTLIDAQWVLTAAHCFFVTREK- 346

  Fly   187 TAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWL 251
               ||..|.....   .::|:.:.|.|      :|.:|:.:..|::.....||||:|||:|:.
  Rat   347 ---ILEGWKVYAG---TSNLHQLPEAA------SISQIIINGNYTDEQDDYDIALVRLSKPLT-- 397

  Fly   252 QMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG--SSKIKQKAMLHIQPQDQCQEAFYKD 314
            ...::.|.|||.....:.   ......::|:|||:.:.  :|...::..:::....:|.:....|
  Rat   398 LSAHIHPACLPLHGQTFG---LNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYD 459

  Fly   315 TKITLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIY 378
            :.:|  ...||||. ..|.|||.|||||||..|.|    ||: |||||.|.| ..||.....|:|
  Rat   460 SYLT--PRMMCAGDLRGGRDSCQGDSGGPLVCEQN----NRW-YLAGVTSWG-TGCGQKNKPGVY 516

  Fly   379 TRVSSYMDWI----ESTIR 393
            |:|:..:.||    ||.:|
  Rat   517 TKVTEVLPWIYRKMESEVR 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	80/259 (31%)
		Tryp_SPc	133..391	CDD:238113	82/264 (31%)
Tmprss13	NP_001121000.1	WWbp	<1..69	CDD:304964
		SRCR_2	203..292	CDD:292133	2/3 (67%)
		SRCR	216..288	CDD:278931	88/279 (32%)
		Tryp_SPc	297..526	CDD:214473	80/259 (31%)
		Tryp_SPc	298..526	CDD:238113	79/258 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910