DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Habp2

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001001505.2	Gene:	Habp2 / 292126	RGDID:	1302979	Length:	558	Species:	Rattus norvegicus

Alignment Length:	316	Identity:	96/316 - (30%)
Similarity:	151/316 - (47%)	Gaps:	58/316 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 LKLLPRTTPRPPSG-----IDQLPEHPYCGSAFSF-----RLVGGHNTGLFEFPWTTLLEYE--- 152
            :::.|.:....|.|     :.:||....||.....     |:.||..:...:.||...|:..
  Rat   271 VEVCPESDAANPLGSLQEPVMELPGFDSCGKTEMTEHAVKRIYGGFKSTAGKHPWQVSLQTSLPL 335

  Fly   153 TVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHI 217
            |.|..:.:.||.|.|...|:||||||.....::| ..:||:.:.......|....
  Rat   336 TTSMPQGHFCGGSLIHPCWVLTAAHCTDMSTKHL-KVVLGDQDLKKTESHEQTFR---------- 389

  Fly   218 RVTIDRILPHAQYSELNY--RNDIALLRLSRPVNW---LQMQNLEPVCLP----PQRGRYANQLA 273
               :::||.::||:|.:.  .||||||:| :||..   |:.:.::.||||    |         :
  Rat   390 ---VEKILKYSQYNERDEIPHNDIALLKL-KPVGGHCALESKYVKTVCLPSDPFP---------S 441

  Fly   274 GSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGG--EIGVDSCS 336
            |:...:||||.||:...|:....|.:.:.....|......|.  |:.||.:|||.  :.|.|:|.
  Rat   442 GTECHISGWGVTETGEGSRQLLDAKVKLIANALCNSRQLYDH--TIDDSMICAGNLQKPGSDTCQ 504

  Fly   337 GDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
            ||||||||.|.:   |..|||  |:||.|:: ||..  .|:||:|:.:::||::|:
  Rat   505 GDSGGPLTCEKD---GTYYVY--GIVSWGQE-CGKK--PGVYTQVTKFLNWIKTTM 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	86/270 (32%)
		Tryp_SPc	133..391	CDD:238113	87/271 (32%)
Habp2	NP_001001505.2	EGF_CA	71..107	CDD:238011
		KR	191..275	CDD:238056	0/3 (0%)
		Tryp_SPc	312..551	CDD:238113	87/272 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910