DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Tmprss15

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_038944148.1	Gene:	Tmprss15 / 288291	RGDID:	1311046	Length:	1028	Species:	Rattus norvegicus

Alignment Length:	417	Identity:	113/417 - (27%)
Similarity:	168/417 - (40%)	Gaps:	93/417 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CNSVEF--GRGTCIEKKD-CDFYAVDKLMELASKQQCFSRQRPDLVCCPRETN------------ 78
            |...||  ..|.||...: ||.|           |.|  ....|...|.|..|
  Rat   647 CQDDEFQCKDGNCIPMGNLCDSY-----------QHC--SDGSDEAHCVRFLNGTQSNNGLVQFN 698

  Fly    79 --------IIPPLAPRISN------GTTNATSSTTTLKL----LPRTTPRPPSGIDQLP------ 119
                    ...|...:|||      |..:|.||...|..    ..|....|...:...|
  Rat   699 IHNIWHIACAEPWTTQISNEVCHLLGLGSANSSMPILSTGGGPFVRLNEAPNGSLILTPSLQCSQ 763

  Fly   120 --------EHPYCGSAF-----SFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRW 171
                    .|..||...     ..::|||.:|....:||...|.|...||.: ..||||.::..|
  Rat   764 DSLILLQCNHKSCGEKMVTQKVGPKIVGGSDTQAGAWPWVVALYYRDRSGDR-LLCGASLVSSDW 827

  Fly   172 LLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYR 236
            |::||||::.  |||...   .|........:::|.     :|..:|..:|||:.:..|.:....
  Rat   828 LVSAAHCVYR--RNLDPT---RWTAVLGLHMQSNLT-----SPQVVRRVVDRIVINPHYDKRRKV 882

  Fly   237 NDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWG--KTESSGSSKIKQKAML 299
            ||||::.|...||:...  ::|:|||.:...:.   .|....::|||  |..:..:..:.::|.:
  Rat   883 NDIAMMHLEFKVNYTDY--IQPICLPEENQTFT---PGRMCSIAGWGYNKINAGSTVDVLKEADV 942

  Fly   300 HIQPQDQCQEAFYKDTKITLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVS 363
            .:...::||:..   .:..:.:|.:||| .|.|.|||.|||||||..:.|    ||: :|.||.|
  Rat   943 PLVSNEKCQQQL---PEYDITESMLCAGYEEGGTDSCQGDSGGPLMCQEN----NRW-FLVGVTS 999

  Fly   364 IGRKHCGTALFSGIYTRVSSYMDWIES 390
            .| ..|......|:|.|||.:::||.|
  Rat  1000 FG-VQCALPNHPGVYARVSQFIEWIHS 1025

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	12/47 (26%)
		Tryp_SPc	131..388	CDD:214473	80/259 (31%)
		Tryp_SPc	133..391	CDD:238113	83/261 (32%)
Tmprss15	XP_038944148.1	SEA	54..155	CDD:214554
		LDLa	188..221	CDD:238060
		CUB	229..335	CDD:412131
		MAM	351..507	CDD:395504
		CUB	528..635	CDD:395345
		LDLa	647..681	CDD:238060	12/46 (26%)
		Tryp_SPc	789..1025	CDD:238113	82/260 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910