DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss38

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_006246600.1	Gene:	Prss38 / 287358	RGDID:	1565729	Length:	380	Species:	Rattus norvegicus

Alignment Length:	353	Identity:	89/353 - (25%)
Similarity:	139/353 - (39%)	Gaps:	80/353 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 IPPLAPRISNGTTNATSSTT-----------------TLKLLPRTTPRPPSGIDQLP-EHPY--- 123
            :.|::.|......|:.||..                 |..|.|  .|.||....:.| .||:
  Rat    26 VTPVSHRHPKSQPNSLSSDVGRPLSQGLGSDPFSLDGTSALSP--GPAPPHSNIRCPFLHPWPPL 88

  Fly   124 ----------------CGS-AFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRW 171
                            ||. |...:|:||..|...::||...:.|...     :.||.|.:...|
  Rat    89 LWCGREPSLHLFLSSACGQPALHGKLLGGELTIDRKWPWQVSIHYAGF-----HVCGGSILNAYW 148

  Fly   172 LLTAAHCIHTMGRNLTAAI-LGEWNRDTDPDCENDLNGVRECAPPHIR-VTIDRILPHAQYSELN 234
            :||||||.....|..|..: :|..|              .|.|..|.: ..|::::.|..:...:
  Rat   149 VLTAAHCFAREKRLQTFDMYVGITN--------------LEVANKHTQWFEINQVIIHPTFEMFH 199

  Fly   235 -YRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG-SSKIKQKA 297
             ...|:||::....:  :....:.|:|||...    ..|:..:...:|||.....| :.|...:|
  Rat   200 PVGGDVALVQSKSAI--VFSDYVLPICLPSSN----LNLSDLSCWTTGWGMVSPQGETGKDLLEA 258

  Fly   298 MLHIQPQDQCQEAFYKDTKITLADSQMCAGGEIGVDS-CSGDSGGPLTVEANTASGNRYVYL-AG 360
            .|.:.|:.||| ..|..|...|.: .:|||....:.: |.||||.||..:.|      ..:| .|
  Rat   259 QLPLIPKFQCQ-LLYGLTSYLLPE-MLCAGDIKNMKNVCEGDSGSPLVCKVN------QTWLQIG 315

  Fly   361 VVSIGRKHCGTALFSGIYTRVSSYMDWI 388
            :||.|| .|...|:.|::..||.:::||
  Rat   316 IVSWGR-GCAQPLYPGVFANVSYFLNWI 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	70/262 (27%)
		Tryp_SPc	133..391	CDD:238113	71/262 (27%)
Prss38	XP_006246600.1	Tryp_SPc	116..343	CDD:238113	71/261 (27%)
Prss38	XP_006246600.1	Tryp_SPc	116..342	CDD:214473	69/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910