DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss45

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_694812.1	Gene:	Prss45 / 260408	MGIID:	3605764	Length:	317	Species:	Mus musculus

Alignment Length:	312	Identity:	87/312 - (27%)
Similarity:	134/312 - (42%)	Gaps:	67/312 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 LKLLPRTTPRPPSGIDQLPEHPYCGSA-FSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGA 164
            |.|||   |||..|.::....|.||:. :...|...|:     :||...|:.|     ..:.||.
Mouse    26 LLLLP---PRPNLGYNENYTEPVCGTPWWPDNLEESHH-----WPWEASLQIE-----DKHVCGG 77

  Fly   165 SFIAQRWLLTAAHCIHTMGRNLTAAILG---------EWNRDTDPDCENDLNGVRECAPPHIRVT 220
            :.|.:.|:::|||||  .|....:.:||         .|.                     :::.
Mouse    78 ALIDRSWVVSAAHCI--QGNKEYSVMLGSSTLHPNGSSWT---------------------LKIP 119

  Fly   221 IDRILPHAQYSELNY-RNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGK 284
            :..|:.|.:|...|: |:|||||.|..||.:  .:.::|:|||...   .|...|:...|:|||:
Mouse   120 VGDIIIHPKYWGRNFIRSDIALLCLETPVTF--NKYVQPICLPEHN---FNFKVGTKCWVTGWGQ 179

  Fly   285 TESSGSSKIKQ-----KAMLHIQPQDQCQEAFYKDT----KITLADSQMCAGGEIGVDSCSGDSG 340
            .:...|:::..     :|.:.|.....|...|:|.|    .:.|....|......|.|.|.||.|
Mouse   180 VKQHSSAQLTPAPELWEAEVFIIDNKNCDSIFHKKTLYPQVVPLIRKNMICTTNYGEDLCYGDPG 244

  Fly   341 GPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
            |||..|.:    .|:: ||||.| ..|.|.|.....:|||::.|..||:..:
Mouse   245 GPLACEID----GRWI-LAGVFS-WEKACATVPNLSVYTRITKYTIWIKDQV 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	74/275 (27%)
		Tryp_SPc	133..391	CDD:238113	75/276 (27%)
Prss45	NP_694812.1	Tryp_SPc	59..289	CDD:238113	75/273 (27%)
Prss45	NP_694812.1	Tryp_SPc	59..286	CDD:214473	73/270 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910