DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and F7

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_690059.1	Gene:	F7 / 260320	RGDID:	628678	Length:	446	Species:	Rattus norvegicus

Alignment Length:	391	Identity:	109/391 - (27%)
Similarity:	164/391 - (41%)	Gaps:	99/391 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NCNSVEFGRGTCI-EKKDCDFYAVDKLMELASKQQCFSRQ----RPDLVCCPRETNIIPPLAPRI 87
            ||...:..:..|. |..|||.|..|   .:.:|:.|...:    :||.|.|          .|::
  Rat   121 NCEKNKNEQLICANENGDCDQYCRD---HVGTKRTCSCHEDYVLQPDEVSC----------KPKV 172

  Fly    88 SNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCG----------SAFSFRLVGGHNTGLFE 142
                                            |:| ||          |....|:|||:.....|
  Rat   173 --------------------------------EYP-CGRIPVVEKRNFSRPQGRIVGGYVCPKGE 204

  Fly   143 FPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGR--NLTAAILGEWNRDTDPDCEND 205
            .||..:|::     .:...|||..:..||::|||||....|:  |:| .:|||.:.......|
  Rat   205 CPWQAVLKF-----NEALLCGAVLLDTRWIVTAAHCFDKFGKLVNIT-VVLGEHDFSEKEGTE-- 261

  Fly   206 LNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYAN 270
                      .:|:....|:|: :|:.....:||||:||.|||.:...  :.|:|| |:|....|
  Rat   262 ----------QVRLVEQVIMPN-KYTRGRTDHDIALVRLHRPVTFTDY--VVPLCL-PERAFSEN 312

  Fly   271 QLAG-SAADVSGWGKTESSGSSKIKQKA--MLHIQPQDQCQEAFYKDTKITLADSQMCAGGEIGV 332
            .||. ..:.|||||:....|::.::...  :..:..||..:.|.:......:.::..|||...|.
  Rat   313 TLASIRFSRVSGWGQLLDRGATALELMVIEVPRLMTQDCLEHAKHSANTPRITENMFCAGYMDGT 377

  Fly   333 -DSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWI----ESTI 392
             |:|.||||||   .|....|.  .||.||||.| :.|......|:|||||.|:||:    :|.:
  Rat   378 KDACKGDSGGP---HATHYHGT--WYLTGVVSWG-EGCAAIGHIGVYTRVSQYIDWLVKYMDSKL 436

  Fly   393 R 393
            |
  Rat   437 R 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	13/49 (27%)
		Tryp_SPc	131..388	CDD:214473	85/262 (32%)
		Tryp_SPc	133..391	CDD:238113	85/267 (32%)
F7	NP_690059.1	GLA	25..85	CDD:214503
		EGF_CA	87..123	CDD:238011	1/1 (100%)
		Tryp_SPc	194..430	CDD:238113	85/263 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910