DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and Prss1

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_036767.1	Gene:	Prss1 / 24691	RGDID:	3417	Length:	246	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	87/282 - (30%)
Similarity:	126/282 - (44%)	Gaps:	57/282 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 GSAFSF------RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMG 183
            |:|.:|      ::|||:.......|:...|.    ||  .:.||.|.|..:|:::||||.
  Rat    11 GAAVAFPLEDDDKIVGGYTCPEHSVPYQVSLN----SG--YHFCGGSLINDQWVVSAAHCY---- 65

  Fly   184 RNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPV 248
            ::.....|||.|.:.....|..:|..             :|:.|..||.....|||.|::||.||
  Rat    66 KSRIQVRLGEHNINVLEGDEQFINAA-------------KIIKHPNYSSWTLNNDIMLIKLSSPV 117

  Fly   249 NWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG--SSKIKQKAMLHIQPQDQCQEAF 311
            .  ....:.||.||.     |...||:...:||||.|.|:|  :..:.|.....:..|..|:.|:
  Rat   118 K--LNARVAPVALPS-----ACAPAGTQCLISGWGNTLSNGVNNPDLLQCVDAPVLSQADCEAAY 175

  Fly   312 YKDTKITLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTAL-- 373
            ..:    :..|.:|.|. |.|.|||.||||||:.....         |.|:||.|   .|.||
  Rat   176 PGE----ITSSMICVGFLEGGKDSCQGDSGGPVVCNGQ---------LQGIVSWG---YGCALPD 224

  Fly   374 FSGIYTRVSSYMDWIESTIRAN 395
            ..|:||:|.:::.||:.||.||
  Rat   225 NPGVYTKVCNFVGWIQDTIAAN 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/261 (30%)
		Tryp_SPc	133..391	CDD:238113	80/262 (31%)
Prss1	NP_036767.1	Tryp_SPc	23..239	CDD:214473	78/261 (30%)
Prss1	NP_036767.1	Tryp_SPc	24..242	CDD:238113	80/263 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910