DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Klk1b3

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_113711.1	Gene:	Klk1b3 / 24594	RGDID:	3175	Length:	265	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	79/273 - (28%)
Similarity:	118/273 - (43%)	Gaps:	44/273 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHT-----MGRNLTAAI 190
            |:|||:|..:...||...:.|     ..:|.||...|...|::|||||...     :|||..
  Rat    28 RVVGGYNCEMNSQPWQVAVYY-----FGEYLCGGVLIDPSWVITAAHCATDNYQVWLGRNNL--- 84

  Fly   191 LGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQN 255
                 .:.:|..::.|  |.: :.||.....|.|..|.:....:|.||:.||.||:|.:  ....
  Rat    85 -----YEDEPFAQHRL--VSQ-SFPHPGFNQDLIWNHTRQPGDDYSNDLMLLHLSQPAD--ITDG 139

  Fly   256 LEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG--SSKIKQKAMLHIQPQDQCQEAFYKDTKIT 318
            ::.:.||.:..:     .||....||||.....|  .|...|...:.:...::|.||.    |..
  Rat   140 VKVIDLPIEEPK-----VGSTCLASGWGSITPDGLELSDDLQCVNIDLLSNEKCVEAH----KEE 195

  Fly   319 LADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVS 382
            :.|..:|||. :.|.|:|.|||||||....         .|.|:.|.|...||.....||||::.
  Rat   196 VTDLMLCAGEMDGGKDTCKGDSGGPLICNG---------VLQGITSWGFNPCGEPKKPGIYTKLI 251

  Fly   383 SYMDWIESTIRAN 395
            .:..||:..::.|
  Rat   252 KFTPWIKEVMKEN 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	76/264 (29%)
		Tryp_SPc	133..391	CDD:238113	77/265 (29%)
Klk1b3	NP_113711.1	Tryp_SPc	28..257	CDD:214473	76/264 (29%)
Klk1b3	NP_113711.1	Tryp_SPc	29..260	CDD:238113	77/266 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910