DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Ctrb1

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_036668.1	Gene:	Ctrb1 / 24291	RGDID:	2444	Length:	263	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	82/270 - (30%)
Similarity:	138/270 - (51%)	Gaps:	44/270 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMG-RNLTAAILGEW 194
            |:|.|.:.....:||...|:.:|   |..: ||.|.|::.|::|||||    | :.....:.||:
  Rat    33 RIVNGEDAIPGSWPWQVSLQDKT---GFHF-CGGSLISEDWVVTAAHC----GVKTSDVVVAGEF 89

  Fly   195 NRDTDPDCENDLNGVRECAPPHIRV-TIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEP 258
            ::.:|.:              :|:| .|.::..:.:::....||||.||:|:.|..:  .:.:..
  Rat    90 DQGSDEE--------------NIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQF--SETVSA 138

  Fly   259 VCLPPQRGRYANQLAGSAADVSGWGKTESSG--SSKIKQKAMLHIQPQDQCQEAFYKDTKITLAD 321
            ||||.....:.   .|:....:|||||:.:.  :.:..|:|.|.|..:..|::::  .:|||  |
  Rat   139 VCLPNVDDDFP---PGTVCATTGWGKTKYNALKTPEKLQQAALPIVSEADCKKSW--GSKIT--D 196

  Fly   322 SQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVY-LAGVVSIGRKHCGTALFSGIYTRVSSYM 385
            ...|||.. ||.||.|||||||..:.:.      |: |||:||.|...|.|:. ..:|:||::.|
  Rat   197 VMTCAGAS-GVSSCMGDSGGPLVCQKDG------VWTLAGIVSWGSGVCSTST-PAVYSRVTALM 253

  Fly   386 DWIESTIRAN 395
            .|::..:.||
  Rat   254 PWVQQILEAN 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	79/261 (30%)
		Tryp_SPc	133..391	CDD:238113	79/262 (30%)
Ctrb1	NP_036668.1	Tryp_SPc	33..256	CDD:214473	79/261 (30%)
Ctrb1	NP_036668.1	Tryp_SPc	34..259	CDD:238113	79/263 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910