DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_663536.1	Gene:	Tmprss11d / 231382	MGIID:	2385221	Length:	417	Species:	Mus musculus

Alignment Length:	309	Identity:	95/309 - (30%)
Similarity:	140/309 - (45%)	Gaps:	50/309 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 LAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTT 147
            :||  ||..|:.|...|...|......||  .:..|.|.         |::||......::||..
Mouse   150 IAP--SNEITSLTDQDTENVLTQECGARP--DLITLSEE---------RIIGGMQAEPGDWPWQV 201

  Fly   148 LLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVREC 212
            .|:...|     :.||.:.|:..|:||||||..:.               .:|.......||...
Mouse   202 SLQLNNV-----HHCGGALISNMWVLTAAHCFKSY---------------PNPQYWTATFGVSTM 246

  Fly   213 APPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAA 277
            : |.:||.:..||.|..||.:...||||:::|.|.|.:  .:|:..||||   ....|.:.||.|
Mouse   247 S-PRLRVRVRAILAHDGYSSVTRDNDIAVVQLDRSVAF--SRNIHRVCLP---AATQNIIPGSVA 305

  Fly   278 DVSGWGKTESSGS--SKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGGEIG-VDSCSGDS 339
            .|:|||.....|:  :.::|..:..|..::....|.|..   ::....:|||...| ||:|.|||
Mouse   306 YVTGWGSLTYGGNAVTNLRQGEVRIISSEECNTPAGYSG---SVLPGMLCAGMRSGAVDACQGDS 367

  Fly   340 GGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWI 388
            ||||..|    ...|..::.|:||.|.: ||.....|:||||::|.:||
Mouse   368 GGPLVQE----DSRRLWFVVGIVSWGYQ-CGLPNKPGVYTRVTAYRNWI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	81/259 (31%)
		Tryp_SPc	133..391	CDD:238113	82/259 (32%)
Tmprss11d	NP_663536.1	SEA	48..140	CDD:279699
		Tryp_SPc	185..411	CDD:214473	81/259 (31%)
		Tryp_SPc	186..414	CDD:238113	82/260 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910