DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss47

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_006517555.1	Gene:	Prss47 / 218304	MGIID:	2685120	Length:	370	Species:	Mus musculus

Alignment Length:	334	Identity:	87/334 - (26%)
Similarity:	147/334 - (44%)	Gaps:	57/334 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 IIPPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLP-EHPYCGS-AFSFRLVGGHNTGLF 141
            ::.|:.|.|.|  .:..|.....:..|:....|.:..:|.| ..|.||. ....::.||.:|...
Mouse    21 LLLPIKPSIPN--ASKVSGIAPGRPQPQQGWEPSASRNQYPVNRPVCGKPKMVGKVFGGQDTLAG 83

  Fly   142 EFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAA------ILGEWNRDTDP 200
            ::||...|.|..|     :.|||..|...||.:.|||.    ||.:.|      :||.
Mouse    84 QWPWQASLLYRGV-----HLCGAVLIDTHWLASTAHCF----RNKSQAPEDYEVLLGN------- 132

  Fly   201 DCENDLNGVRECAPPHIRVTIDRILPHAQYSEL-NYRNDIALLRLSRPVNWLQMQNLEPVCLPPQ 264
                  |.:.:......:::::.|:.|..:.:. ::.:|||:|:|..|:|:...  :.|.|||.:
Mouse   133 ------NQLYQETKHTQKISVNHIVSHPDFEKFHSFGSDIAMLQLHLPINFTSY--VVPACLPSK 189

  Fly   265 RGRYANQLAGSAADVSGWGKTESSGSSKI-----KQKAMLHIQPQDQCQEAFYKDT----KITLA 320
            ..:.:|.   ::..::|||..  |..:|:     .|:..:.|...:.| .|.|..|    :..:.
Mouse   190 DTQLSNH---TSCWITGWGML--SEDTKLLPPFSLQEGEVGIIDNEFC-NALYGQTPGQSRNYVY 248

  Fly   321 DSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSY 384
            :..:|||| ..|...|.|||||||....|:.    :| |.|:.|.| ..|...::..::|||:.:
Mouse   249 EEMLCAGGLSTGKSICRGDSGGPLICYHNST----WV-LVGLASWG-LDCRHPIYPSVFTRVAYF 307

  Fly   385 MDWIESTIR 393
            .|||....|
Mouse   308 TDWISQVKR 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	72/273 (26%)
		Tryp_SPc	133..391	CDD:238113	74/274 (27%)
Prss47	XP_006517555.1	Tryp_SPc	74..314	CDD:238113	74/275 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910