DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and Prss27

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_780649.1	Gene:	Prss27 / 213171	MGIID:	2450123	Length:	328	Species:	Mus musculus

Alignment Length:	280	Identity:	82/280 - (29%)
Similarity:	127/280 - (45%)	Gaps:	40/280 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGSAFSF-RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCI-HTMGRNL 186
            ||....| |:|||.|....|:||...::...:     :.||.|.||..|:||||||. :|...::
Mouse    29 CGHPKMFNRMVGGENALEGEWPWQVSIQRNGI-----HFCGGSLIAPTWVLTAAHCFSNTSDISI 88

  Fly   187 TAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWL 251
            ...:||...             :::..|..:.|.:.::..:.||..:....|:||:.|..||.:.
Mouse    89 YQVLLGALK-------------LQQPGPHALYVPVKQVKSNPQYQGMASSADVALVELQGPVTFT 140

  Fly   252 QMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG---SSKIKQKAMLHIQPQDQCQEAFYK 313
            ..  :.|||||.....:.   :|....|:|||......   :.::.||..:.|....:|...:.|
Mouse   141 NY--ILPVCLPDPSVIFE---SGMNCWVTGWGSPSEQDRLPNPRVLQKLAVPIIDTPKCNLLYNK 200

  Fly   314 DTKI-----TLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTA 372
            |.:.     |:.|..:||| .|...|:|.|||||||....:.:    :|. |||:|.| :.|...
Mouse   201 DVESDFQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVCLVDQS----WVQ-AGVISWG-EGCARR 259

  Fly   373 LFSGIYTRVSSYMDWIESTI 392
            ...|:|.||:|:..||...|
Mouse   260 NRPGVYIRVTSHHKWIHQII 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	76/266 (29%)
		Tryp_SPc	133..391	CDD:238113	77/267 (29%)
Prss27	NP_780649.1	Tryp_SPc	37..275	CDD:214473	76/266 (29%)
Prss27	NP_780649.1	Tryp_SPc	39..278	CDD:238113	77/267 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910