DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prtn3

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_035308.2	Gene:	Prtn3 / 19152	MGIID:	893580	Length:	254	Species:	Mus musculus

Alignment Length:	298	Identity:	76/298 - (25%)
Similarity:	122/298 - (40%)	Gaps:	71/298 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 PSGIDQLPEHPYC-------GSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQ 169
            |.||     ||:.       |:..:.::||||.......|:...|:.....|  .:.||.:.|..
Mouse     8 PKGI-----HPFLLLALVVGGAVQASKIVGGHEARPHSRPYVASLQLSRFPG--SHFCGGTLIHP 65

  Fly   170 RWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELN 234
            |::||||||:..:...|...:||          .:||   ....|...:.||.::..:....|.|
Mouse    66 RFVLTAAHCLQDISWQLVTVVLG----------AHDL---LSSEPEQQKFTISQVFQNNYNPEEN 117

  Fly   235 YRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG-SSKIKQKAM 298
            . ||:.||:|:|..:   :.....|...||:.:..:|  |:.....|||:..:.. :.::.|:
Mouse   118 L-NDVLLLQLNRTAS---LGKEVAVASLPQQDQTLSQ--GTQCLAMGWGRLGTQAPTPRVLQE-- 174

  Fly   299 LHIQPQDQCQEAFYKDTKITL--ADSQMC------AGGEIGVDSCSGDSGGPLTVEANTASGNRY 355
            |::             |.:|.  .:..:|      |.|     .|.|||||||....
Mouse   175 LNV-------------TVVTFLCREHNVCTLVPRRAAG-----ICFGDSGGPLICNG-------- 213

  Fly   356 VYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIR 393
             .|.||.|...:.|.:..|...:.|||.|:|||::.:|
Mouse   214 -ILHGVDSFVIRECASLQFPDFFARVSMYVDWIQNVLR 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	67/265 (25%)
		Tryp_SPc	133..391	CDD:238113	69/266 (26%)
Prtn3	NP_035308.2	Tryp_SPc	29..245	CDD:214473	67/265 (25%)
Prtn3	NP_035308.2	Tryp_SPc	30..248	CDD:238113	69/267 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910