DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Klk6

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001158168.1	Gene:	Klk6 / 19144	MGIID:	1343166	Length:	253	Species:	Mus musculus

Alignment Length:	233	Identity:	75/233 - (32%)
Similarity:	117/233 - (50%)	Gaps:	38/233 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 CGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILP 226
            ||...|..:|:||||||   ...|| ..|||:.|             :|:......::::||.:.
Mouse    54 CGGVLIDPQWVLTAAHC---KKPNL-QVILGKHN-------------LRQTETFQRQISVDRTIV 101

  Fly   227 HAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSS 291
            |.:|:...:.|||.::.|..||.:  .:.::|:   |.:...:.:  .....:.||||.|:....
Mouse   102 HPRYNPETHDNDIMMVHLKNPVKF--SKKIQPL---PLKNDCSEE--NPNCQILGWGKMENGDFP 159

  Fly   292 KIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRY 355
            ...|.|.:|:.|::||:.|:  ..|||  .|.:|||. :.|.|||.|||||||      ..|.|
Mouse   160 DTIQCADVHLVPREQCERAY--PGKIT--QSMVCAGDMKEGNDSCQGDSGGPL------VCGGR- 213

  Fly   356 VYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIR 393
              |.|:||.|...||:....|:||.|.:::.||::.:|
Mouse   214 --LRGLVSWGDMPCGSKEKPGVYTDVCTHIRWIQNILR 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	72/226 (32%)
		Tryp_SPc	133..391	CDD:238113	74/229 (32%)
Klk6	NP_001158168.1	Tryp_SPc	28..244	CDD:214473	72/226 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910