DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Proc

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_006525784.1	Gene:	Proc / 19123	MGIID:	97771	Length:	484	Species:	Mus musculus

Alignment Length:	410	Identity:	117/410 - (28%)
Similarity:	161/410 - (39%)	Gaps:	107/410 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CNSVEFGRGTCIE-----KKDCDFYAVDKLMELASK-QQCFSRQRPDLVCCPRETNIIPPLAPRI 87
            |:|...|.||||:     ...||.....|..:...: |.|.......|..|..|
Mouse   124 CDSPCCGHGTCIDGIGSFSCSCDKGWEGKFCQQELRFQDCRVNNGGCLHYCLEE----------- 177

  Fly    88 SNGTTNATS-------------STTTL-------------KLLPRTTPRPPSGIDQLPEHPYCGS 126
            |||...|.:             ||...             |:|.|.|...    |:|...|
Mouse   178 SNGRRCACAPGYELADDHMRCKSTVNFPCGKLGRWIEKKRKILKRDTDLE----DELEPDP---- 234

  Fly   127 AFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAIL 191
                |:|.|..|...:.||..:|    :...|..|||...|...|:||||||:.  |.......|
Mouse   235 ----RIVNGTLTKQGDSPWQAIL----LDSKKKLACGGVLIHTSWVLTAAHCVE--GTKKLTVRL 289

  Fly   192 GEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNL 256
            ||::.......|.||:             |..||.|..|:..:..||||||||::|..  ..:.:
Mouse   290 GEYDLRRRDHWELDLD-------------IKEILVHPNYTRSSSDNDIALLRLAQPAT--LSKTI 339

  Fly   257 EPVCLPPQRGRYANQL--AGSAADVSGWGKTESSGSSKIKQK----------AMLHIQPQDQCQE 309
            .|:|||  ....|.:|  ||....|:|||..    |.:||..          ..:.:..:::|.|
Mouse   340 VPICLP--NNGLAQELTQAGQETVVTGWGYQ----SDRIKDGRRNRTFILTFIRIPLVARNECVE 398

  Fly   310 AFYKDTKITLADSQMCAG--GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTA 372
            ..    |..::::.:|||  |:.. |:|.||||||:.|.....     .:|.|:||.| :.||..
Mouse   399 VM----KNVVSENMLCAGIIGDTR-DACDGDSGGPMVVFFRGT-----WFLVGLVSWG-EGCGHT 452

  Fly   373 LFSGIYTRVSSYMDWIESTI 392
            ...||||:|.||:.||.|.|
Mouse   453 NNYGIYTKVGSYLKWIHSYI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	13/50 (26%)
		Tryp_SPc	131..388	CDD:214473	85/270 (31%)
		Tryp_SPc	133..391	CDD:238113	86/271 (32%)
Proc	XP_006525784.1	GLA	50..110	CDD:214503
		EGF_CA	111..155	CDD:238011	10/30 (33%)
		FXa_inhibition	163..198	CDD:373209	8/45 (18%)
		Tryp_SPc	236..470	CDD:238113	86/271 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910