DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and Plg

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_032903.3	Gene:	Plg / 18815	MGIID:	97620	Length:	812	Species:	Mus musculus

Alignment Length:	363	Identity:	106/363 - (29%)
Similarity:	155/363 - (42%)	Gaps:	98/363 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 GTTNATSSTTTLK------------LLPRTTPRP---------PSGIDQLP-------------- 119
            |.|..|::.|..:            ..|:|.||.         |.|....|
Mouse   491 GKTAVTAAGTPCQGWAAQEPHRHSIFTPQTNPRAGLEKNYCRNPDGDVNGPWCYTTNPRKLYDYC 555

  Fly   120 EHPYCGSAFSF--------------RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQR 170
            :.|.|.||.||              |:|||.......:||.  :...|...|:.: ||.:.||..
Mouse   556 DIPLCASASSFECGKPQVEPKKCPGRVVGGCVANPHSWPWQ--ISLRTRFTGQHF-CGGTLIAPE 617

  Fly   171 WLLTAAHCIHTMGR-NLTAAILG---EWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYS 231
            |:||||||:....| .....|||   |:.|..|         |:|       :::.:::     .
Mouse   618 WVLTAAHCLEKSSRPEFYKVILGAHEEYIRGLD---------VQE-------ISVAKLI-----L 661

  Fly   232 ELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESS-GSSKIKQ 295
            |.|.| |||||:||||..  ....:.|.|||......|::   :...::|||:|:.: |:.::|:
Mouse   662 EPNNR-DIALLKLSRPAT--ITDKVIPACLPSPNYMVADR---TICYITGWGETQGTFGAGRLKE 720

  Fly   296 KAMLHIQPQDQCQEAFYKDTKITLADSQMCAG---GEIGVDSCSGDSGGPLTVEANTASGNRYVY 357
             |.|.:.....|....|.:.::  ..:::|||   |  |||||.|||||||.    ....::|:
Mouse   721 -AQLPVIENKVCNRVEYLNNRV--KSTELCAGQLAG--GVDSCQGDSGGPLV----CFEKDKYI- 775

  Fly   358 LAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIRAN 395
            |.||.|.| ..|......|:|.|||.::||||..:|.|
Mouse   776 LQGVTSWG-LGCARPNKPGVYVRVSRFVDWIEREMRNN 812

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	84/264 (32%)
		Tryp_SPc	133..391	CDD:238113	86/265 (32%)
Plg	NP_032903.3	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		KR	183..262	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		KR	480..562	CDD:214527	13/70 (19%)
		Tryp_SPc	581..805	CDD:214473	84/264 (32%)
		Tryp_SPc	582..807	CDD:238113	85/265 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910