DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Gzmm

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_032530.1	Gene:	Gzmm / 16904	MGIID:	99549	Length:	264	Species:	Mus musculus

Alignment Length:	271	Identity:	72/271 - (26%)
Similarity:	112/271 - (41%)	Gaps:	38/271 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 GSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAA 189
            |:.|..:::||........|:...|:     ..|.:.||...:.::|:||||||:....:|| ..
Mouse    20 GNRFETQIIGGREAVPHSRPYMASLQ-----KAKSHVCGGVLVHRKWVLTAAHCLSEPLQNL-KL 78

  Fly   190 ILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQ 254
            :||             |:.:.:...|.:...|...:.|..|:. .|.||:|||:|.|.|.  ..:
Mouse    79 VLG-------------LHNLHDLQDPGLTFYIREAIKHPGYNH-KYENDLALLKLDRRVQ--PSK 127

  Fly   255 NLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG-SSKIKQKAMLHIQPQDQCQEA-FYKDTKI 317
            |::|:.||  |...:....|:....:|||.|...| .::..|:..|.:.....|..: |:..
Mouse   128 NVKPLALP--RKPRSKPAEGTWCSTAGWGMTHQGGPRARALQELDLRVLDTQMCNNSRFWNG--- 187

  Fly   318 TLADSQMC-AGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRV 381
            .|.||.:| ..|......|.|||||||........        |::|...|.|.......:.|.|
Mouse   188 VLIDSMLCLKAGSKSQAPCKGDSGGPLVCGKGQVD--------GILSFSSKTCTDIFKPPVATAV 244

  Fly   382 SSYMDWIESTI 392
            :.|..||...|
Mouse   245 APYSSWIRKVI 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	67/259 (26%)
		Tryp_SPc	133..391	CDD:238113	69/260 (27%)
Gzmm	NP_032530.1	Tryp_SPc	27..254	CDD:238113	69/261 (26%)
Gzmm	NP_032530.1	Tryp_SPc	27..251	CDD:214473	67/258 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910