DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Klk1b1

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_034775.1	Gene:	Klk1b1 / 16623	MGIID:	892019	Length:	261	Species:	Mus musculus

Alignment Length:	288	Identity:	84/288 - (29%)
Similarity:	125/288 - (43%)	Gaps:	47/288 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 GIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHC 178
            |||..|       ....|:|||........||     :..|...|:|.||...:...|:||||||
Mouse    14 GIDAAP-------PVQSRIVGGFKCEKNSQPW-----HVAVYRYKEYICGGVLLDANWVLTAAHC 66

  Fly   179 IHTMGRNLTAAILGEWNRDTD-PDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALL 242
            .:....    ..||:.|...| |..::.|.. :....|...:::.|  ...|..:.:|..|:.||
Mouse    67 YYEKNN----VWLGKNNLYQDEPSAQHRLVS-KSFLHPCYNMSLHR--NRIQNPQDDYSYDLMLL 124

  Fly   243 RLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGK--TESSGSSKIKQKAMLHIQPQD 305
            |||:|.:...:  ::|:.||.:..:     .||....||||.  ......:|..|...|.:.|.:
Mouse   125 RLSKPADITDV--VKPIALPTEEPK-----LGSTCLASGWGSIIPVKFQYAKDLQCVNLKLLPNE 182

  Fly   306 QCQEAFYKDTKITLADSQMCA---GGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRK 367
            .|.:|:.:  |:|  |..:||   ||  |.|:|.|||||||..:.         .|.|:.|.|..
Mouse   183 DCDKAYVQ--KVT--DVMLCAGVKGG--GKDTCKGDSGGPLICDG---------VLQGLTSWGYN 232

  Fly   368 HCGTALFSGIYTRVSSYMDWIESTIRAN 395
            .||.....|:||::..:..||:.|:..|
Mouse   233 PCGEPKKPGVYTKLIKFTSWIKDTLAQN 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	76/262 (29%)
		Tryp_SPc	133..391	CDD:238113	77/263 (29%)
Klk1b1	NP_034775.1	Tryp_SPc	24..253	CDD:214473	76/262 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910