DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Klk1b5

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_032482.1	Gene:	Klk1b5 / 16622	MGIID:	892020	Length:	261	Species:	Mus musculus

Alignment Length:	295	Identity:	86/295 - (29%)
Similarity:	124/295 - (42%)	Gaps:	61/295 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 GIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHC 178
            |||..|       ....|:.||.|......||...:...|     .|.||...:...|:||||||
Mouse    14 GIDAAP-------PVQSRIFGGFNCEKNSQPWQVAVYRFT-----KYQCGGVLLNANWVLTAAHC 66

  Fly   179 IHT------MGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRN 237
             |.      :|:|       .:..| :|..::.|...   |.||....:..:..|....|.:|.|
Mouse    67 -HNDKYQVWLGKN-------NFFED-EPSAQHRLVSK---AIPHPDFNMSLLNEHTPQPEDDYSN 119

  Fly   238 DIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKA----- 297
            |:.||||.:|.:...:  ::|:.||.:..:     .||....||||    |.:..|.:.|
Mouse   120 DLMLLRLKKPADITDV--VKPIDLPTEEPK-----LGSTCLASGWG----SITPVIYEPADDLQC 173

  Fly   298 -MLHIQPQDQCQEAFYKDTKITLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLAG 360
             ...:.|.:.|.:|..:  |:|  |..:|||. :.|.|:|.|||||||..:.         .|.|
Mouse   174 VNFKLLPNEDCVKAHIE--KVT--DVMLCAGDMDGGKDTCMGDSGGPLICDG---------VLHG 225

  Fly   361 VVSIGRKHCGTALFSGIYTRVSSYMDWIESTIRAN 395
            :.|.|...||.....||||::..:..||:.||..|
Mouse   226 ITSWGPSPCGKPNVPGIYTKLIKFNSWIKDTIAKN 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	77/269 (29%)
		Tryp_SPc	133..391	CDD:238113	78/270 (29%)
Klk1b5	NP_032482.1	Tryp_SPc	24..253	CDD:214473	77/269 (29%)
Klk1b5	NP_032482.1	Tryp_SPc	25..256	CDD:238113	78/271 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910