DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Klk1

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_034769.4	Gene:	Klk1 / 16612	MGIID:	102850	Length:	261	Species:	Mus musculus

Alignment Length:	296	Identity:	87/296 - (29%)
Similarity:	125/296 - (42%)	Gaps:	63/296 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 GIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHC 178
            |||..|       ....|:|||.|......||...:...|     .|.||...:...|:||||||
Mouse    14 GIDAAP-------PVQSRIVGGFNCEKNSQPWQVAVYRFT-----KYQCGGILLNANWVLTAAHC 66

  Fly   179 IHT------MGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRN 237
             |.      :|:|...        :.:|..::.|...   |.||....:..:..|....|.:|.|
Mouse    67 -HNDKYQVWLGKNNFL--------EDEPSAQHRLVSK---AIPHPDFNMSLLNEHTPQPEDDYSN 119

  Fly   238 DIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIK-------Q 295
            |:.||||.:|.:...:  ::|:.||.:..:     .||....||||..     :.:|       |
Mouse   120 DLMLLRLKKPADITDV--VKPIDLPTEEPK-----LGSTCLASGWGSI-----TPVKYEYPDELQ 172

  Fly   296 KAMLHIQPQDQCQEAFYKDTKITLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLA 359
            ...|.:.|.:.|.:|..:  |:|  |..:|||. :.|.|:|:|||||||..:.         .|.
Mouse   173 CVNLKLLPNEDCAKAHIE--KVT--DDMLCAGDMDGGKDTCAGDSGGPLICDG---------VLQ 224

  Fly   360 GVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIRAN 395
            |:.|.|...||.....||||||.::..||..|:..|
Mouse   225 GITSWGPSPCGKPNVPGIYTRVLNFNTWIRETMAEN 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	79/270 (29%)
		Tryp_SPc	133..391	CDD:238113	80/271 (30%)
Klk1	NP_034769.4	Tryp_SPc	24..253	CDD:214473	79/270 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910