DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Gzmg

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_034505.1	Gene:	Gzmg / 14944	MGIID:	109253	Length:	248	Species:	Mus musculus

Alignment Length:	266	Identity:	71/266 - (26%)
Similarity:	122/266 - (45%)	Gaps:	44/266 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 LVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNR 196
            ::|||.......|:...::...:.|.|.| ||...:...::||||||   ..|::|.. ||..|.
Mouse    21 IIGGHEVKPHSRPYMAFIKSVDIEGKKKY-CGGFLVQDDFVLTAAHC---RNRSMTVT-LGAHNI 80

  Fly   197 DTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCL 261
            ....:.:.             .:.:.:.:||..::..:..|||.||:|.....  :.:.:.|:.|
Mouse    81 KAKEETQQ-------------IIPVAKAIPHPAFNRKHGTNDIMLLKLESKAK--RTKAVRPLKL 130

  Fly   262 PPQRGRYANQLAGSAADVSGWGKTE---SSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQ 323
            |....|..   .|....|:|||||.   :..|::::: |.|.||..::|::.:|..:|.|    |
Mouse   131 PRPNARVK---PGDVCSVAGWGKTSINATKASARLRE-AQLIIQEDEECKKLWYTYSKTT----Q 187

  Fly   324 MCAGGEIGVDS-CSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDW 387
            :|||....|.: ..|:|||||..: |.|        .||||.|   ....:..|::|:|..::.|
Mouse   188 ICAGDPKKVQAPYEGESGGPLVCD-NLA--------YGVVSYG---INRTITPGVFTKVVHFLPW 240

  Fly   388 IESTIR 393
            |.:.::
Mouse   241 ISTNMK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	69/259 (27%)
		Tryp_SPc	133..391	CDD:238113	71/261 (27%)
Gzmg	NP_034505.1	Tryp_SPc	20..241	CDD:214473	69/259 (27%)
Gzmg	NP_034505.1	Tryp_SPc	21..244	CDD:238113	71/262 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910