DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Gzmf

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_034504.1	Gene:	Gzmf / 14943	MGIID:	109254	Length:	248	Species:	Mus musculus

Alignment Length:	265	Identity:	72/265 - (27%)
Similarity:	116/265 - (43%)	Gaps:	42/265 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 LVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNR 196
            ::|||.......|:...:.: ....||.::||...:...::||||||..:..|    .|||..|
Mouse    21 IIGGHEVKPHSRPYMARVRF-VKDNGKRHSCGGFLVQDYFVLTAAHCTGSSMR----VILGAHN- 79

  Fly   197 DTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCL 261
                        :|........:.:.:.:||..|.:.:..:||.||:|.....  :.:.:.|:.|
Mouse    80 ------------IRAKEETQQIIPVAKAIPHPAYDDKDNTSDIMLLKLESKAK--RTKAVRPLKL 130

  Fly   262 PPQRGRYANQLAGSAADVSGWGKTESSGS--SKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQM 324
            |....|..   .|....|:|||:|..:.:  |...::|.|.||...:|::.|||..|    ..|:
Mouse   131 PRPNARVK---PGHVCSVAGWGRTSINATQRSSCLREAQLIIQKDKECKKYFYKYFK----TMQI 188

  Fly   325 CAGGEIGVDSC-SGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWI 388
            |||....:.|. ||||||||..       |...|  ||::.|   ....:..|::|:|..|:.||
Mouse   189 CAGDPKKIQSTYSGDSGGPLVC-------NNKAY--GVLTYG---LNRTIGPGVFTKVVHYLPWI 241

  Fly   389 ESTIR 393
            ...::
Mouse   242 SRNMK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	70/258 (27%)
		Tryp_SPc	133..391	CDD:238113	72/260 (28%)
Gzmf	NP_034504.1	Tryp_SPc	20..241	CDD:214473	70/258 (27%)
Gzmf	NP_034504.1	Tryp_SPc	21..244	CDD:238113	72/261 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910