DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CG43742

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001261130.1	Gene:	CG43742 / 14462622	FlyBaseID:	FBgn0263999	Length:	474	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	78/277 - (28%)
Similarity:	118/277 - (42%)	Gaps:	54/277 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTA 188
            |....::|:..||.....:|       ...:....::.||.|.|.::::||||||:..:..  ..
  Fly    27 CKVKITYRVANGHTAITSQF-------MAALYNNSEFFCGGSLIHKQYVLTAAHCVRDLDE--VT 82

  Fly   189 AILGEWNRDTD-PDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQ 252
            ..|||.||... |.|:            |:.....:::.|..:....:.||||||||.|.|  :.
  Fly    83 VHLGENNRSCPIPVCK------------HVLRLNAKVILHPNFHGNIFLNDIALLRLEREV--IF 133

  Fly   253 MQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKI 317
            ..::.|:|:.......:|......|  .||||||....|.:.....|...|:..|.:..
  Fly   134 EAHIRPICIILDEDVTSNNQNNFTA--YGWGKTEHGNISDVLSFIDLVRLPKSMCYQNI------ 190

  Fly   318 TLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVY-------LAGVVSIGRKHCGTALFS 375
                :.:|||...| |:|..||||||.       || :|:       |.|:.|.|...| :.||
  Fly   191 ----NTICAGSTSG-DTCESDSGGPLI-------GN-FVHRGKSRDILFGITSYGDAEC-SGLF- 240

  Fly   376 GIYTRVSSYMDWIESTI 392
            |:||.|::|..||.|.:
  Fly   241 GVYTDVNAYKSWIASVV 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	74/264 (28%)
		Tryp_SPc	133..391	CDD:238113	75/265 (28%)
CG43742	NP_001261130.1	Tryp_SPc	34..253	CDD:214473	74/264 (28%)
		Tryp_SPc	35..256	CDD:238113	75/266 (28%)
		Tryp_SPc	273..467	CDD:214473
		Tryp_SPc	273..>368	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910