DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and F2

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_034298.1	Gene:	F2 / 14061	MGIID:	88380	Length:	618	Species:	Mus musculus

Alignment Length:	284	Identity:	86/284 - (30%)
Similarity:	131/284 - (46%)	Gaps:	51/284 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWN 195
            |:|.|.:......||..:|..::   .::..||||.|:.||:|||||||          :...|:
Mouse   360 RIVEGWDAEKGIAPWQVMLFRKS---PQELLCGASLISDRWVLTAAHCI----------LYPPWD 411

  Fly   196 RDTDPDCENDLNGVRECAPPHIRV----------TIDRILPHAQYS-ELNYRNDIALLRLSRPVN 249
            ::.   .||||. ||  ...|.|.          .:::|..|.:|: ..|...|||||:|.:||.
Mouse   412 KNF---TENDLL-VR--IGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVP 470

  Fly   250 WLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIK-------QKAMLHIQPQDQC 307
            :  ...:.|||||.::...:...||....|:|||....:.::.|.       |...|.|..:..|
Mouse   471 F--SDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVC 533

  Fly   308 QEAFYKDTKITLADSQMCAGGEIG----VDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKH 368
            :.:    |:|.:.|:..|||.::.    .|:|.||||||..::  :...||: |..|:||.| :.
Mouse   534 KAS----TRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMK--SPFNNRW-YQMGIVSWG-EG 590

  Fly   369 CGTALFSGIYTRVSSYMDWIESTI 392
            |......|.||.|.....||:..|
Mouse   591 CDRKGKYGFYTHVFRLKRWIQKVI 614

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	83/278 (30%)
		Tryp_SPc	133..391	CDD:238113	84/279 (30%)
F2	NP_034298.1	GLA	25..89	CDD:214503
		KR	107..189	CDD:214527
		KR	213..295	CDD:214527
		Thrombin_light	313..360	CDD:286482	86/284 (30%)
		Tryp_SPc	360..610	CDD:214473	83/278 (30%)
		Tryp_SPc	361..613	CDD:238113	84/280 (30%)
		High affinity receptor-binding region which is also known as the TP508 peptide. /evidence=ECO:0000250	548..570		10/21 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910