DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Klk1b9

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_034246.1	Gene:	Klk1b9 / 13648	MGIID:	95293	Length:	261	Species:	Mus musculus

Alignment Length:	287	Identity:	86/287 - (29%)
Similarity:	131/287 - (45%)	Gaps:	45/287 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 GIDQLPE-HPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAH 177
            |||..|. |.        |:|||........||     :..|....:|.||...:...|:|||||
Mouse    14 GIDAAPPVHS--------RIVGGFKCEKNSQPW-----HVAVYRYNEYICGGVLLDANWVLTAAH 65

  Fly   178 CIHTMGRNLTAAILGEWN-RDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIAL 241
            |.:...:    ..||:.| .:.:|..::.|.......|.:.| ::.|  .|.::.|.:|.||:.|
Mouse    66 CYYEENK----VSLGKNNLYEEEPSAQHRLVSKSFLHPGYNR-SLHR--NHIRHPEYDYSNDLML 123

  Fly   242 LRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTE--SSGSSKIKQKAMLHIQPQ 304
            ||||:|.:...:  ::|:.||.:..:     .||....||||.|.  ...::|..|...|.:.|.
Mouse   124 LRLSKPADITDV--VKPIALPTEEPK-----LGSTCLASGWGSTTPFKFQNAKDLQCVNLKLLPN 181

  Fly   305 DQCQEAFYKDTKITLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKH 368
            :.|.:|..:  |:|  |..:||| .:.|.|:|.|||||||..:.         .|.|:.|.|...
Mouse   182 EDCGKAHIE--KVT--DVMLCAGETDGGKDTCKGDSGGPLICDG---------VLQGITSWGFTP 233

  Fly   369 CGTALFSGIYTRVSSYMDWIESTIRAN 395
            ||.....|:||::..:..||:.|:..|
Mouse   234 CGEPKKPGVYTKLIKFTSWIKDTMAKN 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	77/260 (30%)
		Tryp_SPc	133..391	CDD:238113	78/261 (30%)
Klk1b9	NP_034246.1	Tryp_SPc	24..253	CDD:214473	77/260 (30%)
Klk1b9	NP_034246.1	Tryp_SPc	25..256	CDD:238113	78/262 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910