DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Ctsg

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_031826.1	Gene:	Ctsg / 13035	MGIID:	88563	Length:	261	Species:	Mus musculus

Alignment Length:	264	Identity:	73/264 - (27%)
Similarity:	118/264 - (44%)	Gaps:	41/264 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWN 195
            :::||.......:|:...|..::..|..  |||...:.:.::||||||   :|.::... ||..|
Mouse    20 KIIGGREARPHSYPYMAFLLIQSPEGLS--ACGGFLVREDFVLTAAHC---LGSSINVT-LGAHN 78

  Fly   196 RDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVC 260
            ..           :||....  .:|:.|.:.|..|:..|.||||.||:|.|...  :..:::||.
Mouse    79 IQ-----------MRERTQQ--LITVLRAIRHPDYNPQNIRNDIMLLQLRRRAR--RSGSVKPVA 128

  Fly   261 LPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMC 325
            ||....:..   .|....|:|||:...|..:.:.|:..|.:|....|...|    :...:.:|:|
Mouse   129 LPQASKKLQ---PGDLCTVAGWGRVSQSRGTNVLQEVQLRVQMDQMCANRF----QFYNSQTQIC 186

  Fly   326 AGGEIGVDSC-SGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIE 389
            .|......|. .||||||| |.:|.|.        |:||.|..:...   ..::|::.|:|.||:
Mouse   187 VGNPRERKSAFRGDSGGPL-VCSNVAQ--------GIVSYGSNNGNP---PAVFTKIQSFMPWIK 239

  Fly   390 STIR 393
            .|:|
Mouse   240 RTMR 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	69/257 (27%)
		Tryp_SPc	133..391	CDD:238113	71/258 (28%)
Ctsg	NP_031826.1	Tryp_SPc	20..238	CDD:214473	69/257 (27%)
Ctsg	NP_031826.1	Tryp_SPc	21..241	CDD:238113	71/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910