DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP001395

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_321740.5	Gene:	AgaP_AGAP001395 / 1281782	VectorBaseID:	AGAP001395	Length:	268	Species:	Anopheles gambiae

Alignment Length:	288	Identity:	96/288 - (33%)
Similarity:	138/288 - (47%)	Gaps:	48/288 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCI-----HTMG 183
            |||. ..|:|||.|:...:..:...|   |..||  :.||||.:..||||||.||:     ..:.
Mosquito     5 CGSQ-QQRIVGGVNSNRGQITYIASL---TKRGG--HFCGASIVNDRWLLTAGHCVCSGVNKILR 63

  Fly   184 RNLTAAILGEWNR--------DTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIA 240
            .|...|:||.:.|        |:||..:.           ...|.|..|:||..|......||||
Mosquito    64 ANQIQAVLGLYRRSEFGGNQIDSDPFSDR-----------AYEVGIRTIVPHPGYVCNKPSNDIA 117

  Fly   241 LLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIK----QKAMLHI 301
            ||.|:|.:::  ..::.|:||.......| ::.|..|.|:|||..:.:.:...|    |:|::.:
Mosquito   118 LLELARRIDF--SASVRPICLSSGADGSA-RVEGQTAVVAGWGWQQENRNLGDKADTLQRAVVDV 179

  Fly   302 QPQDQCQEAFYKDTKI-TLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSI 364
            ...::|:..:.:..:. |:|.:|:||| |..|||:|..||||||....|.        |.|:||.
Mosquito   180 FRNEECESMYRRGNRSRTIARTQLCAGKGTGGVDACWADSGGPLVTSDNV--------LIGIVST 236

  Fly   365 GRKHCGTALFSGIYTRVSSYMDWIESTI 392
            | ..|....|.|||||||.|..||.:.|
Mosquito   237 G-IGCARPGFPGIYTRVSEYASWIVTVI 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	90/275 (33%)
		Tryp_SPc	133..391	CDD:238113	91/276 (33%)
AgaP_AGAP001395	XP_321740.5	Tryp_SPc	11..259	CDD:214473	90/275 (33%)
AgaP_AGAP001395	XP_321740.5	Tryp_SPc	12..259	CDD:238113	89/274 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910