DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and AgaP_AGAP011719

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_320793.4	Gene:	AgaP_AGAP011719 / 1280920	VectorBaseID:	AGAP011719	Length:	762	Species:	Anopheles gambiae

Alignment Length:	269	Identity:	80/269 - (29%)
Similarity:	122/269 - (45%)	Gaps:	49/269 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 EFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAI--LGEWNR-DTDPDCE 203
            ||.....:.:....|...:.||.|.|.:.::||||||.......|:..:  :|:.|. |.|.|
Mosquito    29 EFAHIAAIGWTQPDGTVQWKCGGSLIWENYILTAAHCYADPDTILSPDVIRIGDLNLFDADDD-- 91

  Fly   204 NDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRY 268
               ..|:|       ..|.:|:.|..::......|:|||:|.:.|  :|.:.:.|.||     ..
Mosquito    92 ---EFVQE-------RKIVQIIRHPLHNASTVYYDLALLKLDKKV--IQSEGVIPTCL-----WL 139

  Fly   269 ANQLAGSAADVSGWGKTESSGSSKIKQ----KAMLHIQPQDQCQEAFYKDTK----ITLADSQMC 325
            .:.:..|..:|:|||:|   |..|.|.    ||.|.:....:|.:...|.|:    ..|||.|:|
Mosquito   140 DDSIPFSTLEVAGWGQT---GFGKEKSNMLLKAELKLMTNTECAKYNNKRTQRRLGNDLADHQLC 201

  Fly   326 AGGEIGVDSCSGDSGGPLTVEANTASGNRYV------YLAGVVSIGRKHCGTALFSGIYTRVSSY 384
            |..|: :|:|.|||||||..       |.|.      :|.||.|.| |.|..:. .|:|.:|:.:
Mosquito   202 AWDEV-MDTCPGDSGGPLHY-------NLYYKHTKIPFLVGVTSFG-KACAVSQ-PGVYVKVAKF 256

  Fly   385 MDWIESTIR 393
            ..||..|::
Mosquito   257 KQWIIETLQ 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	77/262 (29%)
		Tryp_SPc	133..391	CDD:238113	79/265 (30%)
AgaP_AGAP011719	XP_320793.4	Tryp_SPc	19..263	CDD:238113	79/265 (30%)
		Tryp_SPc	19..260	CDD:214473	77/262 (29%)
		Tryp_SPc	318..537	CDD:304450
		Tryp_SPc	653..>762	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910