DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP009211

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_319989.4	Gene:	AgaP_AGAP009211 / 1280170	VectorBaseID:	AGAP009211	Length:	265	Species:	Anopheles gambiae

Alignment Length:	274	Identity:	97/274 - (35%)
Similarity:	133/274 - (48%)	Gaps:	26/274 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTA 188
            ||......:..|.....:.|||..|||   .|...|..||.|.|:.|.:||||||:....|:...
Mosquito     1 CGVTRVQLIAYGQPARAYAFPWMALLE---TSVSDDLPCGGSLISDRHILTAAHCVKARKRDCDD 62

  Fly   189 AILGEWNRDTDPDC--ENDLNGVR---ECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPV 248
            .|   ..:|.:.|.  ..:.:|..   .|.||..|:.|:.|:.|.:||..:.|||:|::||..|.
Mosquito    63 RI---HFKDDEYDSGESEEADGAEYSASCGPPAQRIPIETIVTHPKYSARSKRNDLAIIRLQYPA 124

  Fly   249 NWLQMQNLEPVCLPPQRGRYANQL-AGSAAD--VSGWGKTESSGSSKIKQKAMLHIQPQDQCQEA 310
              :...|:.|:|||     ...|| |...||  |:|||.||:...|.:.:.|:|...|...|...
Mosquito   125 --IIGYNVIPICLP-----LTEQLRAYRPADSFVTGWGLTETGQRSAVLRYAILPALPLPDCAMR 182

  Fly   311 FYK-DTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALF 374
            ..: |..|.|.|..:||||......|.|||||||..   .:...|:| |.||||.|.|.|||.:.
Mosquito   183 IKELDRIIVLDDGHLCAGGNNRTAHCHGDSGGPLQY---VSDSTRFV-LQGVVSFGVKTCGTKIA 243

  Fly   375 SGIYTRVSSYMDWI 388
            .|::..|:.::|||
Mosquito   244 PGVFANVTHFIDWI 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	93/265 (35%)
		Tryp_SPc	133..391	CDD:238113	95/265 (36%)
AgaP_AGAP009211	XP_319989.4	Tryp_SPc	9..257	CDD:214473	93/264 (35%)
AgaP_AGAP009211	XP_319989.4	Tryp_SPc	9..257	CDD:238113	93/264 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920