DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP006539

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_316577.4	Gene:	AgaP_AGAP006539 / 1277138	VectorBaseID:	AGAP006539	Length:	270	Species:	Anopheles gambiae

Alignment Length:	289	Identity:	81/289 - (28%)
Similarity:	136/289 - (47%)	Gaps:	53/289 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 RTTPRPPSGIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQR 170
            |:|....||.|:             |:|.|.:..:.::|:  :|.....:||  ::||.|.:::.
Mosquito    23 RSTIVDESGPDR-------------RIVNGTDASILDYPF--MLSLRGSTGG--HSCGGSILSEL 70

  Fly   171 WLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELN- 234
            |.:|||||:.:....|....:|..|...|.|  :.:.|:.:            ::.|.||...|
Mosquito    71 WAMTAAHCVSSTTTYLQTIQVGRTNISRDVD--DSVYGIAQ------------VIAHPQYDSRNS 121

  Fly   235 YRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIK-QKAM 298
            :.||||||:|.||:  :..::::||.||.......:.|......:.|||...:.||:... |:..
Mosquito   122 HLNDIALLKLQRPI--VFSESVQPVRLPAPMFEVEDDLDDLGVTLIGWGLLATGGSAPATLQRVD 184

  Fly   299 LHIQPQDQCQEAFYKDTKITLADSQMCA---GGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAG 360
            .::.|.::| .|.:..   |:..|.:||   ||  |...|||||||||.         .:....|
Mosquito   185 YYVVPNEEC-NAIHTG---TIYPSHICAAIPGG--GKGQCSGDSGGPLL---------HHGVQVG 234

  Fly   361 VVSIGRKHCGTALFSGIYTRVSSYMDWIE 389
            :||...|.|..|.:.|:.|:||.::::|:
Mosquito   235 IVSWSVKPCAVAPYPGVLTKVSHHLEFIQ 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	75/261 (29%)
		Tryp_SPc	133..391	CDD:238113	75/262 (29%)
AgaP_AGAP006539	XP_316577.4	Tryp_SPc	35..262	CDD:214473	75/261 (29%)
AgaP_AGAP006539	XP_316577.4	Tryp_SPc	36..265	CDD:238113	75/263 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910