DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP006192

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_316257.4	Gene:	AgaP_AGAP006192 / 1276857	VectorBaseID:	AGAP006192	Length:	346	Species:	Anopheles gambiae

Alignment Length:	284	Identity:	77/284 - (27%)
Similarity:	119/284 - (41%)	Gaps:	36/284 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGSAFSFR---LVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRN 185
            ||.....:   :.||..:....:||...:.:........|.||.:.|.:..:|||.||:....|.
Mosquito    26 CGQVQVLKQGLIFGGTASTPGMWPWHVAVFHRESIRRTSYKCGGTIINRDTVLTAYHCVVENQRP 90

  Fly   186 LTAAIL----GEWNRDT-DPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLS 245
            :.|..|    |.::.|. .|..:.  |.|.:...|          |.|  |...:.:|||:|::.
Mosquito    91 IAAGRLVARAGLFDLDVGGPTVQE--NRVFDVISP----------PGA--SARTFDDDIAILKMQ 141

  Fly   246 RPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEA 310
              ..:.....::|||:...| :...||.|:...|.|||.||.|.:|...::|.:.:...:.|..:
Mosquito   142 --TQFTYDDYVQPVCIRSVR-QDIGQLVGAYGTVVGWGWTEQSTTSAELRQANVPVVSAEDCLAS 203

  Fly   311 FYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVS---IGRKHCGTA 372
            ........|.....|||...|..||:|||||.:...   .||  |.:|.|:.|   :..|..|..
Mosquito   204 DRNLFSQVLTTKVYCAGSRNGTSSCNGDSGGGMFFR---MSG--YWFLRGLTSFSAVDAKQSGIC 263

  Fly   373 LFSGI--YTRVSSYMDWI-ESTIR 393
            ...|.  ||.|:.|:||: |..:|
Mosquito   264 DSHGYVGYTDVAKYLDWLREQGVR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	72/269 (27%)
		Tryp_SPc	133..391	CDD:238113	74/268 (28%)
AgaP_AGAP006192	XP_316257.4	Tryp_SPc	37..284	CDD:238113	73/268 (27%)
AgaP_AGAP006192	XP_316257.4	Tryp_SPc	37..280	CDD:214473	71/264 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910