DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP005594

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_315604.2	Gene:	AgaP_AGAP005594 / 1276280	VectorBaseID:	AGAP005594	Length:	294	Species:	Anopheles gambiae

Alignment Length:	329	Identity:	72/329 - (21%)
Similarity:	120/329 - (36%)	Gaps:	94/329 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 NATSSTTTLKLLPRTTPRPPSGIDQLPEH----------PYCGSAFSFRLVGGHNTGLFEFPWTT 147
            |.:::...:|:.|.:        |:.||.          ||..||..:.   |:|....:||:..
Mosquito    19 NTSAALDVIKVNPMS--------DETPEGFKTMSAGTVVPYTYSATYWY---GYNAYAGQFPYHA 72

  Fly   148 LLEYETVSGGKDYACGASFIAQRWLLTAAHCIH-------------TMGR--NLTAAILGEWNRD 197
            .:.:.|  ....|....:.|...:::|.|...|             |:|.  |.|.    :|
Mosquito    73 EINFYT--NNYLYKRAGALITLNYVITPASSFHHYFIHGDMLYGYITLGSVFNSTT----QW--- 128

  Fly   198 TDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLP 262
                 |..:|........|         |...|:..:|.| ||::||.||.  :|.:.::|:.||
Mosquito   129 -----EQTINYTESSIVMH---------PFFHYTNEDYYN-IAIIRLDRPA--IQTRYVKPIRLP 176

  Fly   263 PQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAM-LHIQPQDQCQEAFYKDTKITLADSQMCA 326
                :.::.....|.:.:..|.|:..|.|.::...: |.|     |::..   |..|..|...|.
Mosquito   177 ----KLSDTRTYLAMEGTSCGTTKEEGLSYLRNPLLSLSI-----CRQQL---TSYTFHDQHYCT 229

  Fly   327 GGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYT------RVSSYM 385
            ....|...|:...|..||||.....     .|.|||.:        ||...|:      |:|::.
Mosquito   230 DVYRGGSFCNRQCGSSLTVEDENGP-----VLIGVVDL--------LFQCSYSYPVRYVRLSAFR 281

  Fly   386 DWIE 389
            :||:
Mosquito   282 EWIQ 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	60/278 (22%)
		Tryp_SPc	133..391	CDD:238113	62/279 (22%)
AgaP_AGAP005594	XP_315604.2	Tryp_SPc	60..285	CDD:304450	61/275 (22%)
AgaP_AGAP005594	XP_315604.2	Tryp_SPc	60..284	CDD:214473	60/274 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910