DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and AgaP_AGAP005194

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_314093.2	Gene:	AgaP_AGAP005194 / 1274900	VectorBaseID:	AGAP005194	Length:	272	Species:	Anopheles gambiae

Alignment Length:	299	Identity:	77/299 - (25%)
Similarity:	129/299 - (43%)	Gaps:	70/299 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 EHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTM-- 182
            :||....|.:: :|.|.:......|:...|:.:..|     .|..|.:..||:|||.||:..:
Mosquito    23 DHPISPFAANY-IVDGSDAEENAAPYQVSLQIDGNS-----TCSGSIVGDRWILTAEHCVPLLQF 81

  Fly   183 ---GRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSEL--------NYR 236
               ..|.|..:.|          .|||   ::...|:.   |||...:...|.:        :..
Mosquito    82 FSERSNNTRVVAG----------TNDL---KKGGTPYF---IDRFFNYDNCSTMLVHTFMFNSTP 130

  Fly   237 NDIALLRLSRPVNWLQ-MQNLEPVCLPPQRGRYANQLA--GSAADVSGWGKTESSGSSKIKQKAM 298
            |||||:||:.|:.:.| ::.:|          :..:..  .:...::|||:.. :|:|..|.:.:
Mosquito   131 NDIALIRLTTPLKFNQRVKKIE----------FTTETVPENATLTLTGWGQMR-NGTSPAKLQTI 184

  Fly   299 ----LHIQPQDQCQEAFYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLA 359
                :.|   |.|: |.|.:|  .|.|..:|:..:.|..:|.||||||:|.:..         |.
Mosquito   185 NAPSIRI---DHCR-AIYNET--YLNDGTICSLSKRGEGACMGDSGGPVTWKGK---------LV 234

  Fly   360 GVV-SIGRKHCGTALFSGIYTRVSSYMDWIESTIRANRI 397
            |:. ::..|.||.. |..|:|.|:.|..||:.||..|.:
Mosquito   235 GIFKAVHNKGCGEG-FPDIHTSVAYYYKWIKDTIANNSV 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	69/277 (25%)
		Tryp_SPc	133..391	CDD:238113	71/278 (26%)
AgaP_AGAP005194	XP_314093.2	Tryp_SPc	34..266	CDD:238113	71/279 (25%)
AgaP_AGAP005194	XP_314093.2	Tryp_SPc	34..263	CDD:214473	69/276 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910