DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP005072

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_313947.4	Gene:	AgaP_AGAP005072 / 1274755	VectorBaseID:	AGAP005072	Length:	857	Species:	Anopheles gambiae

Alignment Length:	304	Identity:	84/304 - (27%)
Similarity:	123/304 - (40%)	Gaps:	73/304 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CG---SAFSFRLVGGHNTGLFEFPWTTLLEYETVSGG----KDYACGASFIAQRWLLTAAHCIHT 181
            ||   .|...|:..|.......:||         .||    .||.||.:.|.:.::|||:||:
Mosquito    49 CGVPKIALRSRITDGGVADEGHWPW---------HGGLFHLNDYQCGCTLINELFVLTASHCV-- 102

  Fly   182 MGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRV------------------TIDRILPHA 228
                        :|.||.......|          :||                  |:.:|:||:
Mosquito   103 ------------YNSDTGYKISEKL----------VRVRLGMHRLSANGSSAVQTYTVQKIIPHS 145

  Fly   229 QYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKI 293
            ::....:::|:|||||:..|.:...  ::||||......:...||.....|.|||.||.:..|..
Mosquito   146 KFVPNTHKHDVALLRLNGTVKFTNY--IQPVCLDLTESIWVEYLADVYGTVVGWGLTEKNRISDQ 208

  Fly   294 KQKAMLHIQPQDQCQEAFYKDTKITLADSQM-CAGGEIGVDSCSGDSGGPLTVEANTASGNRYVY 357
            ..||.|.|.....|.|: ..|....|..|.| |||...|...|:|||||.:.:...    ||: :
Mosquito   209 LLKAELPIVRYTDCVES-NPDLYGRLIYSGMYCAGILNGTSPCNGDSGGGMYIFRE----NRW-F 267

  Fly   358 LAGVVSI-----GRKHCGTALFSGIYTRVSSYMDWIESTIRANR 396
            |.||||.     |..:|.:..:. ::..|..|..||.:.:.|.|
Mosquito   268 LRGVVSFSGIREGTNYCDSFSYV-VFMNVPYYAKWIGTEVDAAR 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	77/284 (27%)
		Tryp_SPc	133..391	CDD:238113	78/285 (27%)
AgaP_AGAP005072	XP_313947.4	Tryp_SPc	59..302	CDD:214473	77/284 (27%)
		Tryp_SPc	60..302	CDD:238113	76/283 (27%)
		IG_like	373..447	CDD:214653
		IGc2	377..436	CDD:197706
		LamG	451..600	CDD:238058
		LamG	673..826	CDD:238058
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910