DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP004570

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_313874.5	Gene:	AgaP_AGAP004570 / 1274709	VectorBaseID:	AGAP004570	Length:	259	Species:	Anopheles gambiae

Alignment Length:	274	Identity:	96/274 - (35%)
Similarity:	146/274 - (53%)	Gaps:	38/274 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGSA-FSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLT 187
            ||:| ...|:|||..||:.::||...|.|:     ..:.||||.:.:.::||||||:..:.||..
Mosquito    13 CGAANQEIRIVGGRPTGVNQYPWLARLVYD-----GQFHCGASLLTKDYVLTAAHCVRRLKRNKI 72

  Fly   188 AAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQ 252
            ..|||::::....:            .|.|...:..|:.|..:.:.:|.:|||||:|.:||.:
Mosquito    73 RVILGDYDQFVASE------------TPAIMRAVTAIIRHRSFDQNSYNHDIALLKLRKPVEF-- 123

  Fly   253 MQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGS-SKIKQKAMLHIQPQDQCQEAFYKDTK 316
            .:.:.|||||.:|...|.||    ..|.|||:|...|: ..:.|...:.|...|||:...|:.::
Mosquito   124 TKTIRPVCLPKERSEPAGQL----GTVVGWGRTSEGGTLPALVQHVDVPILTLDQCRSMKYRASR 184

  Fly   317 ITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRV 381
            ||   |.|...|:...|||.|||||||.|.    :|::: .:.|:||.| ..||.|.:.|:||||
Mosquito   185 IT---SNMLCAGKGKQDSCQGDSGGPLLVR----NGDKH-EIVGIVSWG-VGCGRAGYPGVYTRV 240

  Fly   382 SSYMDWIESTIRAN 395
            :.|:.|    :|||
Mosquito   241 ARYLPW----LRAN 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	89/257 (35%)
		Tryp_SPc	133..391	CDD:238113	89/258 (34%)
AgaP_AGAP004570	XP_313874.5	Tryp_SPc	21..246	CDD:214473	89/256 (35%)
AgaP_AGAP004570	XP_313874.5	Tryp_SPc	22..250	CDD:238113	90/263 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910