DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP004552

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_313850.5	Gene:	AgaP_AGAP004552 / 1274693	VectorBaseID:	AGAP004552	Length:	349	Species:	Anopheles gambiae

Alignment Length:	274	Identity:	98/274 - (35%)
Similarity:	130/274 - (47%)	Gaps:	35/274 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGSA--FSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNL 186
            |||.  .:.|:|||.......|.|...|.|:     ..:.||.|.::.|:::|||||.....|.|
Mosquito   101 CGSVEPINERIVGGIPVEDNSFSWMAALYYD-----NKFCCGGSLLSDRYVITAAHCTTKPDRGL 160

  Fly   187 TAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWL 251
            .....|             :|...:.....|..::.|||.: .|:..|..||||||.|:.||  .
Mosquito   161 FRVQFG-------------INDRSKPIATSIERSVKRILTN-WYNAFNNNNDIALLELTYPV--A 209

  Fly   252 QMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGS-SKIKQKAMLHIQPQDQCQEAFYKDT 315
            ....:.|:|||.....|    .||...|:|||:|::.|. |....:..:.|....:|:.|.|...
Mosquito   210 ISDRVMPICLPQATEMY----EGSRGIVTGWGRTKAGGGLSGTLMQTEVPILTNRECRRAGYWAF 270

  Fly   316 KITLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYT 379
            :||  :..:|||. |.|.|||.|||||||.| .||.| |.| .|.||||.||. |....|.|:|.
Mosquito   271 QIT--NKMLCAGYLEGGKDSCQGDSGGPLQV-LNTKS-NHY-ELVGVVSWGRA-CAQKNFPGVYA 329

  Fly   380 RVSSYMDWIESTIR 393
            |||.|:.||...|:
Mosquito   330 RVSQYLYWINRNIK 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	92/258 (36%)
		Tryp_SPc	133..391	CDD:238113	93/259 (36%)
AgaP_AGAP004552	XP_313850.5	Tryp_SPc	110..338	CDD:214473	92/258 (36%)
AgaP_AGAP004552	XP_313850.5	Tryp_SPc	111..341	CDD:238113	93/260 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910