DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP003626

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_313388.5	Gene:	AgaP_AGAP003626 / 1274290	VectorBaseID:	AGAP003626	Length:	305	Species:	Anopheles gambiae

Alignment Length:	320	Identity:	84/320 - (26%)
Similarity:	135/320 - (42%)	Gaps:	90/320 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 KLLPRTT--PRPPSGI----DQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDY 160
            |::.||.  ..||:|:    .:.|.....|..|                      ||...   |.
Mosquito    44 KVIDRTNVFDTPPNGLPAREGEFPHQVRVGQWF----------------------YEDED---DT 83

  Fly   161 A----CGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTI 221
            |    |..:.|:.|::|.||||:.|:|....:....::.|          ||..    |.:.:..
Mosquito    84 AFILRCSGALISDRYVLIAAHCLWTLGDEEVSLGRHDYTR----------NGTF----PELSIKR 134

  Fly   222 DRILPHAQYSE---LNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWG 283
            |.::.|..|.|   .:| |||||:||::||.:  ..::.|.||..:.         .||:.:
Mosquito   135 DDLILHPSYDEQTKASY-NDIALVRLAQPVTF--TSHIYPACLWTEE---------EAAEPT--- 184

  Fly   284 KTESSGSS-----KIKQKAMLHIQ----PQDQCQEAF----YKDTKITLADSQMCAGGEIGVDS- 334
            |..|||.:     |::...::.||    |..:|...:    |....:|  |:.:||...:...|
Mosquito   185 KLTSSGFTMGRLGKLRDTRLVKIQVSRVPNAECSREYTDSGYYPQGVT--DALLCAESPVEWKSL 247

  Fly   335 CSGDSGGPL-TVEANTASGNRYVY-LAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
            |.||:||.| |::.::|.    || |.||.:.|.: |..:....|:|:|...:|||||.:
Mosquito   248 CEGDAGGLLQTLDRDSAD----VYRLIGVEAKGHE-CDQSHQKFIFTKVRQQLDWIESVV 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	71/279 (25%)
		Tryp_SPc	133..391	CDD:238113	74/280 (26%)
AgaP_AGAP003626	XP_313388.5	Tryp_SPc	57..301	CDD:238113	78/304 (26%)
AgaP_AGAP003626	XP_313388.5	Tryp_SPc	57..298	CDD:214473	75/301 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910