DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CLIPB5

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_313032.4	Gene:	CLIPB5 / 1273975	VectorBaseID:	AGAP004148	Length:	379	Species:	Anopheles gambiae

Alignment Length:	412	Identity:	148/412 - (35%)
Similarity:	206/412 - (50%)	Gaps:	65/412 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LLLIP-LFLTLLGAEAQQ--------FGKAIMHFGNCNSVEFGRGTCIEKKDCDFYAVDKLMELA 57
            |.|:| |.||||...|.|        .|:.|: ..||||:.    |.|.||.    .:|......
Mosquito    14 LQLVPFLLLTLLSISAAQQCTLPDSTVGECIL-LRNCNSLL----TLIRKKP----LLDADRTYL 69

  Fly    58 SKQQC--FSRQRPDLVCCPRETNIIPPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPE 120
            .:.||  .:.:...||||  ..:::.|:  |:                          |:..||.
Mosquito    70 QRSQCGWSAAENHPLVCC--ADSLVAPV--RV--------------------------GVGLLPS 104

  Fly   121 HPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGR- 184
            ...||...|.|:.||.||.:.||||..||:|...:....:.||...|..|::|||:||::  |:
Mosquito   105 PGQCGIQTSDRIFGGVNTRIDEFPWIALLKYAKPNNVFGFHCGGVLINDRYVLTASHCVN--GKD 167

  Fly   185 -----NLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQY--SELNYRNDIALL 242
                 ||....||||:..|..|||. |....:|:||.|.|.|:..:||.:|  :.....||||||
Mosquito   168 IPSTWNLAEVRLGEWDTSTAQDCEG-LGDDVDCSPPPIDVPIEGKIPHPEYVPTSAEQYNDIALL 231

  Fly   243 RLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQC 307
            ||.:.|.:...  ::|:|||.|....|....|....|:|||:|.::..|.:|||..:.....|.|
Mosquito   232 RLQQSVPYSDF--IKPICLPMQAELKARDYVGFRMQVAGWGRTATARFSNVKQKVAVDGVSLDAC 294

  Fly   308 QEAFYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTA 372
            .:.:.:: ::.|..||:|||||.|.|||.|||||||| ..:||.|.:|.||.|:||.|...||.|
Mosquito   295 NQVYQRE-QVLLRQSQLCAGGEAGKDSCQGDSGGPLT-GVHTAGGLQYWYLIGLVSFGPTPCGQA 357

  Fly   373 LFSGIYTRVSSYMDWIESTIRA 394
            .:.|:||:|..|:|||.:||.|
Mosquito   358 GWPGVYTKVDQYVDWITATIAA 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	13/46 (28%)
		Tryp_SPc	131..388	CDD:214473	108/264 (41%)
		Tryp_SPc	133..391	CDD:238113	109/265 (41%)
CLIPB5	XP_313032.4	CLIP	33..87	CDD:288855	15/62 (24%)
		Tryp_SPc	115..373	CDD:214473	108/264 (41%)
		Tryp_SPc	116..373	CDD:238113	107/263 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	1	1.000	-	-		FOG0003849
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920