DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP003248

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_312959.4	Gene:	AgaP_AGAP003248 / 1273921	VectorBaseID:	AGAP003248	Length:	296	Species:	Anopheles gambiae

Alignment Length:	288	Identity:	96/288 - (33%)
Similarity:	145/288 - (50%)	Gaps:	27/288 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 PSGIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAA 176
            |:....||:.|.||:....||:......|.|.||..|:||...:|...|.||.|.|.:|:::|||
Mosquito    28 PAQKSLLPQPPMCGNDAPERLITSLVAQLDEAPWMALIEYWKPNGSLSYLCGGSLINERYVVTAA 92

  Fly   177 HCIHTMGRNLTA--AILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYS--ELNYRN 237
            ||:.::.:..|.  ..||||:..|..||::.     .|....|.|.:|:|..|..|.  ..|:||
Mosquito    93 HCVTSLPQGWTVHRIRLGEWDLSTSEDCDHS-----RCNDAPIDVAVDKITVHEDYKSPSRNHRN 152

  Fly   238 DIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESS--GSSKIK-QKAML 299
            ||||:||.|.:::  .:.:.|:|| ||.|....|...:...| ||.:....  |..|:: ::.::
Mosquito   153 DIALIRLDRQMHY--TETVAPICL-PQNGPLQTQRYRTMHSV-GWIEENFGPIGGKKLQVEQDLV 213

  Fly   300 HIQPQDQCQEAFYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSI 364
            ..|   .| .:.|....|.|||:|:|...:  .|:....:||||   ....:|:.|::  ||.|.
Mosquito   214 DFQ---NC-SSNYLQASIALADTQLCVAQQ--KDNRIDIAGGPL---MQRIAGHWYLF--GVASF 267

  Fly   365 GRKHCGTALFSGIYTRVSSYMDWIESTI 392
            |.::.||.....:||.|..|:|||||.|
Mosquito   268 GGRNYGTVELPNVYTNVMEYVDWIESNI 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	85/263 (32%)
		Tryp_SPc	133..391	CDD:238113	86/264 (33%)
AgaP_AGAP003248	XP_312959.4	Tryp_SPc	53..291	CDD:214473	83/257 (32%)
AgaP_AGAP003248	XP_312959.4	Tryp_SPc	54..294	CDD:238113	86/259 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.880