DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CLIPD6

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_312099.2	Gene:	CLIPD6 / 1273147	VectorBaseID:	AGAP002813	Length:	484	Species:	Anopheles gambiae

Alignment Length:	408	Identity:	123/408 - (30%)
Similarity:	182/408 - (44%)	Gaps:	71/408 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 AIMHFGNCNSVEFGRGTCIEKKDCDFYAVDKLMELASKQQ-----CFSRQ--------RPDLVCC 73
            |.:...:|...:...|.||..:.|.    |.|.|...:|:     .:.||        :|: |||
Mosquito   107 APLRTADCIGPDNREGYCINIRSCP----DVLNEFVQRQRDPQYVQYIRQSNAVCNYIQPN-VCC 166

  Fly    74 PRETNI--IPPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPY------------- 123
            |.:.:.  .||.||..:..|...|:          ..|.||:.:.|.|..|.
Mosquito   167 PLQKSAPPAPPTAPPTAPPTAPPTA----------PPPPPPAPVTQAPPAPAPSSGPAELLTPET 221

  Fly   124 -CG--SAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRN 185
             ||  :....|:|||....|..:||..|:.|:...|...:.||.|.|.:|.:|||||||.   |:
Mosquito   222 GCGYSTVQHNRVVGGVPAELNGWPWMALVGYKNTLGEVSFKCGGSLITKRHVLTAAHCIR---RD 283

  Fly   186 LTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNW 250
            |::..|||  .||..|.|.          .||.|.:.|...|..|.:.:...|:|:|.:...|.:
Mosquito   284 LSSVRLGE--HDTSTDAET----------KHIDVPVVRYESHPSYDKKDGHTDLAVLYMEFEVQF 336

  Fly   251 LQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG-SSKIKQKAMLHIQPQDQCQEAFYKD 314
              ...::|:|||......:....|....|:|||:|:..| |:.:.|:..:.|...|:|:..:.|.
Mosquito   337 --SDAIKPICLPLSETIRSKNFIGYTPFVAGWGRTQEGGKSANVLQELQIPIIANDECRTLYDKI 399

  Fly   315 TKI----TLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALF 374
            .|:    ...::.||||. |.|.|||.|||||||.:.....: ..|.|..|:||.| ..|..|..
Mosquito   400 GKVFSQKQFDNAVMCAGVIEGGKDSCQGDSGGPLMLPQRFGT-EFYYYQVGIVSYG-IGCARAEV 462

  Fly   375 SGIYTRVSSYMDWIESTI 392
            .|:||||:|::|||:..:
Mosquito   463 PGVYTRVASFVDWIQQKV 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	14/57 (25%)
		Tryp_SPc	131..388	CDD:214473	90/262 (34%)
		Tryp_SPc	133..391	CDD:238113	91/263 (35%)
CLIPD6	XP_312099.2	CLIP	25..80	CDD:288855
		CLIP	114..166	CDD:288855	13/56 (23%)
		Tryp_SPc	232..476	CDD:214473	90/262 (34%)
		Tryp_SPc	233..479	CDD:238113	91/264 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920