DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP010662

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_311382.4	Gene:	AgaP_AGAP010662 / 1272470	VectorBaseID:	AGAP010662	Length:	584	Species:	Anopheles gambiae

Alignment Length:	299	Identity:	84/299 - (28%)
Similarity:	126/299 - (42%)	Gaps:	52/299 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 DQLPEHPY----CGSAFSFR---LVGGHNTGLFEFPWTTLLEYETV-SGGKDYACGASFIAQRWL 172
            |:|..:.|    ||.....|   :.||::|...::||...|.:..: |.|.:||||.|.:.:..:
Mosquito    17 DELHINDYNDNECGERMVKRKGLVKGGYSTQPGDWPWHAALYHRGINSAGFEYACGGSIVHRYLV 81

  Fly   173 LTAAHCI--HTMGRNLTA----AILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYS 231
            ||||||:  .|..|.:.|    ..||.:|.         :|...|.|.   ...:...:.|..|.
Mosquito    82 LTAAHCVTLATSRRKIPAENMQLRLGRFNL---------MNNEEEYAE---EFDVIETIMHEGYR 134

  Fly   232 ELNYRNDIALLRLSRPVNWLQMQNLEPVCL-PPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQ 295
            ...:.||||:||:..|:  :....::|||| ....|............|.|||.:|.:.......
Mosquito   135 PTTFENDIAILRVEIPI--IFNDYIQPVCLWKRDDGVVLPWFYNQPGTVVGWGLSEDNMIGTTLN 197

  Fly   296 KAMLHIQPQDQC---QEAFYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVY 357
            :|.:.:.....|   ..||:..   .|.....|||.:.|...|:|||||.:..:..    ||: |
Mosquito   198 EARMPVVDSWTCLASDRAFFGK---FLQSKAFCAGYKNGTGVCNGDSGGGMFFQFQ----NRW-Y 254

  Fly   358 LAGVVSIGRKHCGTALFSGI--------YTRVSSYMDWI 388
            |.||||..    .|..:||:        :|..|.|:||:
Mosquito   255 LKGVVSFS----NTNDYSGVCNLKQYIGFTDASQYIDWV 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/278 (28%)
		Tryp_SPc	133..391	CDD:238113	78/275 (28%)
AgaP_AGAP010662	XP_311382.4	Tryp_SPc	42..292	CDD:238113	78/274 (28%)
		Tryp_SPc	42..289	CDD:214473	77/272 (28%)
		Tryp_SPc	334..578	CDD:214473
		Tryp_SPc	334..578	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910